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DUSP12

dual specificity phosphatase 12

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

Gene Name: dual specificity phosphatase 12
Family/Subfamily: Protein Phosphatase , LMW-DSP
Synonyms: DUSP12, DUSP 12, HYVH1, YVH1 homolog, YVH1, GKAP
Target Sequences: NM_007240 NP_009171.1 Q9UNI6

☰ Filters
Antibodies (25)
Proteins (5)
Over-Expression Lysate (2)
Primary (25)
Recombinant (3)
DUSP12 (30)
Human (25)
Mouse (14)
Rat (5)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (3)
WB (24)
ELISA (9)
IP (2)
rabbit (24)
mouse (1)
IgG (23)
polyclonal pc (25)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (12)
aa162-191 (7)
aa72-121 (4)
aa1-50 (1)
aa85-284 (1)
No (30)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
DUSP12 Antibody
Select
DUSP12 Rabbit anti-Human Polyclonal (aa85-284) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
DUSP12 Antibody - Immunohistochemistry of paraffin-embedded Human brain using DUSP12 Polyclonal Antibody at dilution of 1:25.
Select
DUSP12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
DUSP12 Rabbit anti-Human Polyclonal (aa162-191) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
DUSP12 Rabbit anti-Human Polyclonal (aa162-191) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
DUSP12 Rabbit anti-Human Polyclonal (aa162-191) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
DUSP12 Rabbit anti-Human Polyclonal (aa162-191) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
DUSP12 Rabbit anti-Human Polyclonal (aa162-191) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
DUSP12 Rabbit anti-Human Polyclonal (aa162-191) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
DUSP12 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using DUSP12 Polyclonal Antibody at dilution of 1:77.
Select
DUSP12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
DUSP12 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
DUSP12 Antibody - Detection of human DUSP12 by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-DUSP12 antibody used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
DUSP12 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IP, WB
Unconjugated
10 µl/$295
Select
DUSP12 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
DUSP12 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
DUSP12 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
DUSP12 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
DUSP12 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
DUSP12 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
DUSP12 Antibody - DUSP12 / GKAP antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DUSP12 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
WB
Unconjugated
100 µl/$424
DUSP12 Antibody - DUSP12 / GKAP antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DUSP12 Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
DUSP12 Antibody - DUSP12 / GKAP antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DUSP12 Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
DUSP12 Antibody - DUSP12 / GKAP antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DUSP12 Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
DUSP12 Antibody - DUSP12 Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The DUSP12 antibody detected the DUSP12 protein (arrow).
Select
DUSP12 Rabbit anti-Human Polyclonal (aa162-191) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
DUSP12 Antibody - Western blot analysis of extracts of various cell lines, using DUSP12 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
Select
DUSP12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DUSP12 Antibody - Western blot analysis of extracts of various cell lines using DUSP12 Polyclonal Antibody at dilution of 1:3000.
Select
DUSP12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
DUSP12 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 30 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).