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Anti-DSP / Desmoplakin Antibody LS-C22821

Ordering

Wt. Vol. Conc. Price
50 µg 1000 µl - $475
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DSP / Desmoplakin Antibodies

Anti-DSP / Desmoplakin Antibody (aa1672-1684) IHC-plus™ LS-B7401
Goat Polyclonal to Human DSP / Desmoplakin
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-DSP / Desmoplakin Antibody (phospho-Ser2849) LS-C209392
Rabbit Polyclonal to Human DSP / Desmoplakin
Human
Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Bovine DSP / Desmoplakin
Bovine, Human, Mouse, Rat, Chicken
IHC - Paraffin, IHC - Frozen
Unconjugated

Details

Bovine DSP / Desmoplakin
Mouse
Bovine, Human, Mouse, Rat, Chicken (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (1:10)
  • IHC - Frozen (1:10)

Specificity and Use

DSP / Desmoplakin antibody was raised against bovine desmoplakin 1.
Recognizes bovine Desmoplakin 1 at 250kD; reacts with the rod fragment of desmoplakin 1. Species cross-reactivity: human, rat, chicken, mouse. Reactivities on cultured human carcinoma cell lines: MCF-7, A-431, TR-146; bovine cells: MDBK, BMGE. Specifically detects tumors on primary and metastatic carcinoma, and meningioma. Shows distinct punctate membrane staining of epithelia.
Immunohistochemistry (frozen and paraffin): 1:10 with PBS, pH 7.4; incubation time 1h at RT. Microwave treatment required.

Packaging

Lyophilized from PBS, pH 7.4, 0.09% sodium azide, 0.5% BSA.
1,000 µl Sterile ddH2O
Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid frequent freeze thaws.
For research use only.

About DSP / Desmoplakin

P15924 NM_004415 NP_004406.2

DSP Antibody, Apeg-1 Antibody, Desmoplakin II Antibody, DP Antibody, Desmoplakin I Antibody, DPI Antibody, Desmoplakin (DPI, DPII) Antibody, KPPS2 Antibody, PPKS2 Antibody, Desmoplakin Antibody, DPII Antibody

Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments.

Requested From: United States
Date Requested: 12/7/2016

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