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Anti-DSP / Desmoplakin Antibody (aa1672-1684) IHC-plus™ LS-B7401

Note: This antibody replaces LS-C139597

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DSP / Desmoplakin Antibodies

Anti-DSP / Desmoplakin Antibody (aa1672-1684) IHC-plus™ LS-B7401
Goat Polyclonal to Human DSP / Desmoplakin
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-DSP / Desmoplakin Antibody (phospho-Ser2849) LS-C209392
Rabbit Polyclonal to Human DSP / Desmoplakin
Human
Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human DSP / Desmoplakin
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human DSP / Desmoplakin
Goat
Human (tested or 100% immunogen sequence identity)
Monkey, Mouse, Rat, Dog, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (3.75 µg/ml)
  • ELISA (1:4000)

Specificity and Use

DSP / Desmoplakin antibody was raised against synthetic peptide C-QESVKQAHLRNEH from an internal region of human DSP / Desmoplakin (NP_004406.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Monkey, Mouse, Rat, Hamster, Elephant, Dog, Horse, Rabbit, Opossum, Platypus (92%); Panda, Bat, Turkey, Chicken (85%).
LS-E27404 - Lyophilized - 100 µg - $145.00
aa1672-1684
Human DSP / Desmoplakin. This antibody is expected to recognize reported isoform I (NP_004406.2) only.
Peptide ELISA: antibody detection limit dilution 1:4000. Western blot: Preliminary experiments in lysates of cell lines HEK293, HeLa and NIH3T3 gave no specific signal but low background (at antibody concentration up to 1 ug/ml).

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About DSP / Desmoplakin

P15924 NM_004415 NP_004406.2

DSP Antibody, Apeg-1 Antibody, Desmoplakin II Antibody, DP Antibody, Desmoplakin I Antibody, DPI Antibody, Desmoplakin (DPI, DPII) Antibody, KPPS2 Antibody, PPKS2 Antibody, Desmoplakin Antibody, DPII Antibody

Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments.

Immunohistochemistry

Immunohistochemistry
Anti-DSP / Desmoplakin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7401 concentration 3.75 ug/ml.
 

Requested From: United States
Date Requested: 12/9/2016

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