Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
DSG2 / Desmoglein 2 antibody was raised against human desmoglein 2.
Recognizes human desmoglein 2 protein (~165kD). Does not cross-react with desmoglein 1 or desmoglein 3 protein.
Suitable for use in Immunoprecipitation, Western Blot and Immunofluorescence. Immunoprecipitation (Native): 5-10 ug. Western Blot: 1-3 ug/ml. Immunofluorescence: 20-50 ug/ml. Positive control: A431 cells.
PBS, pH 7.4, 0.1 % sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
DSG2 Antibody, ARVC10 Antibody, Cadherin family member 5 Antibody, CDHF5 Antibody, CMD1BB Antibody, Desmoglein-2 Antibody, Desmoglein II Antibody, HDGC Antibody, ARVD10 Antibody, Desmoglein 2 Antibody
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18.