Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Bovine (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [DG 3.10]
Protein A purified
IHC - Paraffin (1:10)
IHC - Frozen (1:10)
Specificity and Use
Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis.
Recognizes human, rat, bovine and mouse. Does not react with cells containing plaque-bearing junctions of non-desmosomaltype. Reacts on cultured lines, A-431, MCF-7, TR-146, PLC and various other humanepithelial cell lines; bovine BMGE+H, BMGE-H, and MDBK.