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| Catalog Number | Size | Price |
|---|---|---|
| LS-C22811-50 | 50 µg | $966 |
Monoclonal Mouse anti‑Bovine DSG1+2 / Desmoglein 1+2 Antibody (C‑Terminus, IHC, IF, WB) LS‑C22811
Monoclonal Mouse anti‑Bovine DSG1+2 / Desmoglein 1+2 Antibody (C‑Terminus, IHC, IF, WB) LS‑C22811
Antibody:
DSG1+2 / Desmoglein 1+2 Mouse anti-Bovine Monoclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, IHC-Fr, IF, WB
Reactivity:
Bovine, Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
DSG1+2 / Desmoglein 1+2 Mouse anti-Bovine Monoclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, IHC-Fr, IF, WB
Reactivity:
Bovine, Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
Desmoglein 1+2 antibody LS-C22811 is an unconjugated mouse monoclonal antibody to Desmoglein 1+2 (DSG1+2) (C-Terminus) from bovine. It is reactive with human, mouse, rat and other species. Validated for IF, IHC and WB.
Host
Mouse
Reactivity
Bovine, Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis.
Epitope
C-Terminus
Specificity
Species (tested so far) Human, bovine, rat, mouse. Recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells; does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting: Mr 165000 Desmoglein, 'band 3' polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ('RUD') of the cytoplasmic C-terminal part of the polypeptide. Reactivities on Cultured Cell Lines (tested so far): A-431, MCF-7, TR-146, PLC and various other human epithelial cell lines; bovine BMGE+H, BMGE-H, MDBK.
Applications
- IHC
- IHC - Paraffin
- IHC - Frozen
- Immunofluorescence
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Suitable for use in Immunohistochemistry (frozen sections, paraffin-embedded tissue after microwave treatment), Western Blot; Cryo, Paraffin (Microwave), Immunofluorescence microscopy. Immunohistochemistry: 1:10 with PBS, pH 7.4; Incubation Time 1 h at RT; extended with paraffin.
Presentation
Lyophilized
Reconstitution
Reconstitute in deionized water
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Bovine
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Reactivity:
Monkey
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
