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Anti-DSC3 / Desmocollin 3 Antibody (aa136-695) LS-C150182

Ordering

Wt. Vol. Conc. Price
100 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular DSC3 / Desmocollin 3 Antibodies

Anti-DSC3 / Desmocollin 3 Antibody (clone Dsc3-U114) LS-C85058
Mouse Monoclonal [clone Dsc3-U114] (IgG1) to Human DSC3 / Desmocollin 3
Human
IHC - Paraffin, IHC - Frozen, Western blot
Unconjugated
Anti-DSC3 / Desmocollin 3 Antibody (aa822-850) IHC-plus™ LS-B9474
Rabbit Polyclonal to Human DSC3 / Desmocollin 3
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Sheep Polyclonal (IgG) to Mouse DSC3 / Desmocollin 3
Mouse
IHC, Western blot
Unconjugated

Details

Mouse DSC3 / Desmocollin 3
Sheep
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC (5 - 15 µg/ml)
  • Western blot (1 µg/ml)

Specificity and Use

DSC3 / Desmocollin 3 antibody was raised against mouse myeloma cell line NS0-derived recombinant mouse Desmocollin3 Arg136-Leu695 Accession # P55850.
aa136-695
Detects mouse Desmocollin3 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant.

Packaging

Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 500 ul
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About DSC3 / Desmocollin 3

Q14574 NM_001941 NP_001932.2

DSC3 Antibody, CDHF3 Antibody, Cadherin family member 3 Antibody, Desmocollin-3 Antibody, Desmocollin 3 Antibody, DSC4 Antibody, HT-CP Antibody, Desmocollin-4 Antibody, DSC Antibody

DSC3 / Desmocollin 3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.

Immunohistochemistry

Immunohistochemistry
Desmocollin-3 in Mouse Embryo. Desmocollin-3 was detected in immersion fixed frozen sections of mouse embryo (13 d. p. c.) using Sheep Anti-Mouse Desmocollin-3 Antigen Affinity-purified Polyclonal Antibody at 1.7 ug/ml overnight at 4°C. Tissue was stained using Anti-Sheep HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the epidermis of the developing limb bud.

Western blot

Western blot
Detection of Mouse Desmocollin-3 by Western Blot. Western blot shows lysates of mouse embryo (15 d. p. c.) tissue and mouse skin tissue. PVDF membrane was probed with 1 ug/ml of Sheep Anti-Mouse Desmocollin-3 Antigen Affinity-purified Polyclonal Antibody followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody. Specific bands were detected for Desmocollin-3 at approximately 90-110 kD (as indicated). This experiment was conducted under reducing conditions.

Requested From: United States
Date Requested: 12/2/2016

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