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DRPLA / Atrophin-1
atrophin 1
Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
| Gene Name: | atrophin 1 |
| Synonyms: | ATN1, B37, Atrophin 1, D12S755E, NOD, HRS, Atrophin-1, DRPLA |
| Target Sequences: | NM_001940 NP_001931.2 P54259 |
Publications (1)
1
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth. Jan Krivanek, Ruslan A Soldatov, Maria Eleni Kastriti, Tatiana Chontorotzea, Anna Nele Herdina, Julian Petersen, Bara Szarowska, Marie Landova, Veronika Kovar Matejova, Lydie Izakovicova Holla, Ulrike Kuchler, Ivana Vidovic Zdrilic, Anushree Vijaykumar, Anamaria Balic, Pauline Marangoni, Ophir D Klein, Vitor C M Neves, Val Yianni, Paul T Sharpe, Tibor Harkany, Brian D Metscher, Marc Bajénoff, Mina Mina, Kaj Fried, Peter V Kharchenko, Igor Adameyko. Nature communications. 2020 September;11:4816. [Full Text Article]
[PubMed:32968047]
[PMC:PMC7511944]
Related Antibodies: LS-C352119.
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Myc-DDK (Flag)
125.2 kDa
20 µg/$215
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
100 µl/$299
![DRPLA / Atrophin-1 Antibody - Immunofluorescence of monoclonal antibody to ATN1 on HeLa cell . [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/drpla-atrophin-1-antibody-clone-2c10-ls-c197080/144609_4840574.jpg)
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (2C10) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa38-87) Antibody
Human
WB
Unconjugated
100 µl/$424
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa38-87) (Biotin) Antibody
Rabbit, Mouse, Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa135-180) Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
50 µl/$321; 100 µl/$403
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (50-130 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa81-130) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa1150-C-term) Antibody
Human
IP, WB
Unconjugated
10 µg/$295; 100 µl/$514
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DRPLA / Atrophin-1 Mouse anti-Human Monoclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal (aa879-1190) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
DRPLA / Atrophin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
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