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Anti-DPP4 / CD26 Antibody (RPE) LS-C43463

Note: This antibody replaces LS-C57292

Ordering

Wt. Vol. Conc. Price
- 100 tst - $345
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DPP4 / CD26 Antibodies

Anti-DPP4 / CD26 Antibody (N-Terminus) IHC-plus™ LS-A8059
Rabbit Polyclonal to Human DPP4 / CD26
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-DPP4 / CD26 Antibody IHC-plus™ LS-A8061
Rabbit Polyclonal to Human DPP4 / CD26
Human, Monkey
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human DPP4 / CD26
Human
IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
RPE Conjugated

Details

Human DPP4 / CD26
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
R. Phycoerythrin. Also available Unconjugated.
Purified
Unmodified

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • (applications tested for the base form of this product only)

Specificity and Use

DPP4 / CD26 antibody was raised against human T-cell leukaemia cells (T-CLL).
Recognizes human Dipeptidyl peptidase 4, also known as Adenosine deaminase complexing protein 2, CD26, TP103, ADABP or DPP IV. CD26 is a 766 amino acid ~110 kD single pass type II transmembrane glycoprotein expressed by activated T cells, B cells and macrophages. A soluble form of CD26 can be derived by cleavage of the membrane bound form between residues 38-39. CD26 acts as a functional receptor for the pathogenic Middle East respiratory syndrome coronavirus [MERS-CoV], a severe and frequently fatal disease in humans and marmosets sharing identical CD26 sequence at the site of interaction with the MERS-CoV spike protein. Has been used successfully for the immunohistochemical detection of CD26 on formalin fixed, paraffin embedded tissues and the demonstration of elevated CD26 expression in thyroid neoplasia. Has also been used for the immunohistochemical detection of CD26 on cryostat sections using both immunoperoxidase and immunofluorescence staining in liver biopsies from NASH patients.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. Method sheets are available on request.

Packaging

Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
100 tst Distilled Water.
For research use only.

About DPP4 / CD26

P27487 NM_001935 NP_001926.2

DPP4 Antibody, ADCP-2 Antibody, ADABP Antibody, Dipeptidyl peptidase IV Antibody, Dipeptidyl-peptidase 4 Antibody, DPPIV Antibody, ADCP2 Antibody, T-cell activation antigen CD26 Antibody, CD26 Antibody, CD26 antigen Antibody, Dipeptidyl peptidase 4 Antibody, Dipeptidylpeptidase 4 Antibody, DPP IV Antibody, TP103 Antibody

Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion.

Requested From: United States
Date Requested: 12/8/2016

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