Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC - Frozen
Specificity and Use
DPP4 / CD26 antibody was raised against human CD26.
Recognizes human CD26.
Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Also suitable for studies of CD26-mediated T cell signaling as well as studies of involvement of CD26 in HIV infection. Flow Cytometry: 1 ug/1E6 cells. Immunohistochemistry: Frozen sections.
PBS, 0.1% sodium azide, a stabilizing agent, 40% glycerol.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion.