Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone OX-61] (IgG2a) to Rat DPP4 / CD26
IHC, IHC - Frozen, Flow Cytometry
Rat DPP4 / CD26
Rat (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [OX-61]
Tissue culture supernatant
IHC - Frozen
Flow Cytometry (1:20 - 1:50)
Specificity and Use
DPP4 / CD26 antibody was raised against 110 kD membrane glycoprotein.
CD26. Rat liver antigen dipeptidyl peptidase IV. Reacts with liver bile canicular domains and brush borders of bile ducts. It also recognizes other epithelial brush borders such as a kidney and intestine, MRC OX-61 recognizes T lymphocytes and some B lymphocytes. Clone OX61 has been reported as being suitable for use in western blotting.
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion.