Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone BA5b] (IgG2a) to Human DPP4 / CD26
Human DPP4 / CD26
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [BA5b]
Protein A purified
IHC - Paraffin
Specificity and Use
DPP4 / CD26 antibody was raised against a human T cell clone.
The mouse monoclonal antibody BA5b recognizes CD26, a 110 kD type II membrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages. HLDA VI; WS Code N-L078.
Flow Cytometry: Recommended dilution - 1.5 ug/ml. Positive control - human peripheral blood leukocytes.
PBS, 15 mM sodium azide, pH 7.4
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion.