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Anti-DOK4 Antibody (aa228-258) LS-C99155

Catalog Size Price
LS-C99155-400 400 µl Unavailable

Related Products

23 DOK4 Antibodies

Most Popular DOK4 Antibodies

Anti-DOK4 Antibody (aa11-60) IHC-plus™ LS-B9973
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Immunohistochemistry Image
Anti-DOK4 Antibody (C-Terminus, AP) LS-C276852
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Anti-DOK4 Antibody (C-Terminus) LS-C327212
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Anti-DOK4 Antibody LS-C330844
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Anti-DOK4 Antibody (aa30-110) LS-C383180
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100% Guaranteed
Rabbit Polyclonal to Human DOK4
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human DOK4
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

LS-E9196 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C99155. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa228-258
This DOK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-258 amino acids from the C-terminal region of human DOK4.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About DOK4

Q8TEW6 NM_018110 NP_060580.2

DOK4 Antibody, Docking protein 4 Antibody, Insulin receptor substrate 5 Antibody, IRS5 Antibody, IRS-5 Antibody

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway By similarity. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
Western blot of DOK4 (arrow) using DOK4 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DOK4 gene (Lane 2) (Origene Technologies).

Requested From: 
Date Requested: 10/23/2017

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