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DOK1

docking protein 1, 62kDa (downstream of tyrosine kinase 1)

DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.

Gene Name: docking protein 1, 62kDa (downstream of tyrosine kinase 1)
Synonyms: DOK1, Docking protein 1, Gap binding protein p62dok, p62(dok), p62DOK, Pp62
Target Sequences: NM_001381 NP_001372.1 Q99704

☰ Filters
Antibodies (67)
Proteins (6)
ELISA Kits (3)
Cell-Based (1)
Cell-Based Phosphorylation (2)
Over-Expression Lysate (2)
Primary (67)
Recombinant (4)
DOK1 (76)
Human (62)
Mouse (35)
Rat (43)
Bovine (6)
Chimpanzee (3)
Dog (5)
Horse (8)
Monkey (5)
Pig (5)
IHC (26)
IHC-P (5)
WB (67)
ELISA (22)
ICC (2)
IF (9)
IP (1)
Peptide-ELISA (7)
rabbit (66)
mouse (1)
Product Group
IHCPlus (1)
IgG (49)
polyclonal pc (67)
96-Well Microplate (3)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (44)
aa18-237 (8)
aa9-39 (7)
pTyr398 (7)
pTyr362 (6)
C-Terminus (4)
300-380 aa (2)
340-420 aa (1)
Arg392 (1)
Internal (1)
Tyr362 (1)
aa329-378 (1)
p362 (1)
p398 (1)
No (76)
Adherent Cell Cultures (3)
GST (1)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (4)
Rat (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
DOK1 Antibody - Immunohistochemical analysis of DOK1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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DOK1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
DOK1 Antibody - Anti-DOK1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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DOK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
DOK1 Antibody - 1:100 staining mouse pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DOK1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DOK1 Antibody - 1:100 staining mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DOK1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DOK1 Antibody - Western blot of Dok-1 antibody
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DOK1 Rabbit anti-Human Polyclonal (300-380 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DOK1 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using p62 Dok Antibody. The picture on the right is blocked with the synthesized peptide.
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DOK1 Rabbit anti-Human Polyclonal (aa329-378) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DOK1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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DOK1 Rabbit anti-Human Polyclonal (pTyr362) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DOK1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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DOK1 Rabbit anti-Human Polyclonal (pTyr398) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DOK1 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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DOK1 Rabbit anti-Human Polyclonal (aa9-39) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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DOK1 Rabbit anti-Human Polyclonal (aa9-39) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
DOK1 Rabbit anti-Human Polyclonal (aa9-39) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
DOK1 Rabbit anti-Human Polyclonal (aa9-39) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
DOK1 Rabbit anti-Human Polyclonal (aa9-39) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
DOK1 Rabbit anti-Human Polyclonal (aa9-39) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
DOK1 Rabbit anti-Human Polyclonal (aa9-39) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
DOK1 Antibody - Western blot of Phospho-Dok-1 (Y362) antibody
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DOK1 Rabbit anti-Human Polyclonal (300-380 aa) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
DOK1 Rabbit anti-Human Polyclonal (p362) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
DOK1 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p62Dok (Ab-398) antibody.
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DOK1 Rabbit anti-Human Polyclonal (p398) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
DOK1 Antibody - IHC of Dok-1 (R392) pAb in paraffin-embedded human breast carcinoma tissue.
Select
DOK1 Rabbit anti-Human Polyclonal (Arg392) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
DOK1 Rabbit anti-Human Polyclonal (Tyr362) Antibody
Mouse, Dog, Bovine, Rat, Pig, Horse, Human, Monkey
IHC, WB
Unconjugated
100 µg/$523
Select
DOK1 Rabbit anti-Human Polyclonal Antibody
Mouse, Dog, Bovine, Rat, Pig, Horse, Human, Monkey
IHC, WB
Unconjugated
50 µg/$489
Select
DOK1 Rabbit anti-Human Polyclonal Antibody
Mouse, Dog, Bovine, Rat, Pig, Horse, Human, Monkey
IHC, WB
Unconjugated
50 µg/$489
Select
DOK1 Rabbit anti-Human Polyclonal (pTyr362) Antibody
Mouse, Dog, Bovine, Rat, Pig, Horse, Human, Monkey
IHC, WB
Unconjugated
50 µg/$489
Select
DOK1 Rabbit anti-Human Polyclonal (pTyr398) Antibody
Mouse, Dog, Bovine, Rat, Pig, Horse, Human, Monkey
IHC, WB
Unconjugated
50 µg/$489
DOK1 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using DOK1 Antibody at dilution of 1:100
Select
DOK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 76 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).