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| Catalog Number | Size | Price |
|---|---|---|
| LS-C501214-50 | 50 µg | $294 |
| LS-C501214-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human DOCK7 Antibody (IF, WB) LS‑C501214
Polyclonal Rabbit anti‑Human DOCK7 Antibody (IF, WB) LS‑C501214
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
DOCK7 antibody LS-C501214 is an unconjugated rabbit polyclonal antibody to human DOCK7. Validated for ELISA, IF and WB.
Target
Human DOCK7
Synonyms
DOCK7 | Dedicator of cytokinesis 7 | KIAA1771 | ZIR2
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
Specificity
Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Applications
- Immunofluorescence
- Western blot
- ELISA
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About DOCK7
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
Western blot, Immunoprecipitation
Species:
Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Reactivity:
Human
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
