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Anti-DNMT3A Antibody LS-C6411


Wt. Vol. Conc. Price
100 µg - - $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular DNMT3A Antibodies

Anti-DNMT3A Antibody (aa170-220) IHC-plus™ LS-B7240
Rabbit Polyclonal to Human DNMT3A
Human, Mouse, Bovine, Cat, Horse, Chicken
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-DNMT3A Antibody (C-Terminus, clone 64B1446) LS-C522
Mouse Monoclonal [clone 64B1446] (IgG1) to Mouse DNMT3A
Mouse, Human
IHC, ICC, Western blot, Chromatin Immunoprecipitation
Immunocytochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Mouse DNMT3A
Mouse, Human
Western blot


Mouse DNMT3A
Mouse, Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal


Western blot (2 µg/ml)

Specificity and Use

DNMT3A antibody was raised against bacteria expressed HIS-tag recombinant mouse Dnmt3a.
Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3. Dnmt1 is constitutively expressed in proliferating cells and inactivation o.
Suitable for use in Western Blot. Western Blot: 2 ug/ml.


PBS, 0.02% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About DNMT3A

Q9Y6K1 NM_022552 NP_072046.2

DNMT3A Antibody, DNA MTase HsaIIIA Antibody, DNMT3A2 Antibody, DNA methyltransferase HsaIIIA Antibody, M.HsaIIIA Antibody

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells.

Requested From: United States
Date Requested: 10/28/2016

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