Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Human DNM1L / DRP1
Human, Bovine (tested or 100% immunogen sequence identity)
IHC - Paraffin
(applications tested for the base form of this product only)
Specificity and Use
DNM1L / DRP1 antibody was raised against a synthetic peptide made to an internal region within residues 500-600 of the human protein. [Swiss-Prot# O00429]. Percent identity by BLAST analysis: Bovine (100%).
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
DNM1L Antibody, DYMPLE Antibody, Dynamin 1-like Antibody, Dynamin-like protein Antibody, Dynamin-like protein 4 Antibody, Dynamin-like protein IV Antibody, DLP1 Antibody, Dnm1p/Vps1p-like protein Antibody, DVLP Antibody, Dynamin-related protein 1 Antibody, DYNIV-11 Antibody, DRP1 Antibody, Dynamin-1-like protein Antibody, VPS1 Antibody, EMPF Antibody, HDYNIV Antibody
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage.
Anti-DNM1L antibody IHC of human brain, cerebellum, Purkinje. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7263 concentration 5 ug/ml. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
Lane 1: DRP1 knockout Lane 2: DRP1 wild type MEFs Stained at 1:500x dilution. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
Requested From: United States
Date Requested: 10/26/2016