Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
DNM1L / DRP1 antibody was raised against a synthetic peptide made to an internal region within residues 500-600 of the human protein. [Swiss-Prot# O00429]. Percent identity by BLAST analysis: Bovine (100%).
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
DNM1L Antibody, DYMPLE Antibody, Dynamin 1-like Antibody, Dynamin-like protein Antibody, Dynamin-like protein 4 Antibody, Dynamin-like protein IV Antibody, DLP1 Antibody, Dnm1p/Vps1p-like protein Antibody, DVLP Antibody, Dynamin-related protein 1 Antibody, DYNIV-11 Antibody, DRP1 Antibody, Dynamin-1-like protein Antibody, VPS1 Antibody, EMPF Antibody, HDYNIV Antibody
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage.
Anti-DNM1L antibody IHC of human brain, cerebellum, Purkinje. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7263 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Lane 1: DRP1 knockout Lane 2: DRP1 wild type MEFs Stained at 1:500x dilution. This image was taken for the unconjugated form of this product. Other forms have not been tested.