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Anti-DNM1 / Dynamin Antibody (phospho-Ser778) LS-C242

Note: This antibody replaces LS-C22966

Ordering

Wt. Vol. Conc. Price
- 100 µl - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DNM1 / Dynamin Antibodies

Anti-DNM1 / Dynamin Antibody (phospho-Ser778) LS-C65079
Sheep Polyclonal to Human DNM1 / Dynamin
Human, Mouse, Rat
Western blot
Unconjugated
Anti-DNM1 / Dynamin Antibody (clone 3G4B6) LS-C82109
Mouse Monoclonal [clone 3G4B6] (IgG2a) to Human DNM1 / Dynamin
Human
IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Sheep Polyclonal to Rat DNM1 / Dynamin
Rat, Human, Mouse, Bovine, Dog, Chicken
Western blot
Unconjugated

Details

Rat DNM1 / Dynamin
Sheep
Rat, Human, Mouse, Bovine, Dog, Chicken (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

DNM1 / Dynamin antibody was raised against phosphopeptide corresponding to amino acid residues surrounding the phosphoSer778 of rat dynamin.
pSer778
Specific for the ~95k dynamin protein phosphorylated at Ser778. Labels the purified protein phosphorylated in vitro by cdk5 but not by PKC. Does not cross react with other purified substrates of cdk5 (e. g. amphiphysin and synapsin). Immunolabeling is blocked by X-phosphatase treatment.

Packaging

50 uL of 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol.
Long term: -20°C; Short term: -20°C
For research use only.

About DNM1 / Dynamin

Q05193 NM_004408 NP_004399.2

DNM1 Antibody, Dynamin Antibody, Dynamin-1 Antibody, DNM Antibody, Dynamin 1 Antibody

DNM1 / Dynamin is a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity.

Western blot

Western blot
Western blot of rat hippocampal lysate stimulated with forskolin showing specific immunolabeling of the ~95k dynamin phosphorylated at Ser778 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda phosph
 

Requested From: United States
Date Requested: 12/7/2016

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