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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DNASE2 / DNase II Antibody (C‑Terminus) LS‑C22784 Best Seller
DNase II antibody LS-C22784 is an unconjugated rabbit polyclonal antibody to mouse DNase II (DNASE2). Validated for ELISA.
Antibody
Catalog
Size
Price
LS-C22784-50
50 µg (1 mg/ml)
Unavailable

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Species: Mouse
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Product Description

DNase II antibody LS-C22784 is an unconjugated rabbit polyclonal antibody to mouse DNase II (DNASE2). Validated for ELISA.
About DNASE2 / DNase II
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. O00115 NM_001375 NP_001366.1

DNASE2 Antibody, Acid DNase Antibody, DNase II Antibody, DNase II alpha Antibody, DNASE2A Antibody, Deoxyribonuclease II alpha Antibody, Deoxyribonuclease-2-alpha Antibody, DNase II, lysosomal Antibody, R31240_2 Antibody, DNL Antibody, DNL2 Antibody, Lysosomal DNase II Antibody


Specifications

Target
Mouse DNASE2 / DNase II
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • ELISA (1:10000 - 1:50000)
Immunogen
A 17-aa peptide near the C-terminus of mouse Dnase II (1) was synthesized, coupled to KLH.
Epitope
C-Terminus
Specificity
Recognizes mouse Deoxyribonuclease II (Dnase II). The peptide sequence is not well conserved in human Dnase II. No significant sequence homology with other lysosomal enzymes.
Usage
Suitable for use in ELISA. ELISA: 1:10000-1:50000 using 50-100 ng control peptide/well.
Presentation
Supplied as a liquid in PBS, pH 7.4, 0.1% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/17/2018

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