Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Protein G purified
Western blot (1 - 2 µg/ml)
DNAJA3 / TID1 antibody was raised against recombinant hTid-1 protein. MW of Antigen: 40 and 43kD. Cellular Localization: Mitochondria.
Recognizes both short and long variants of human TID-1 and it co-precipitates mitochondrial Hsp70. Species cross-reactivity: Mouse and rat.
Suitable for use in Immunoprecipitation and Western Blot. Immunoprecipitation: 2 ug/mg protein lysate (Use Protein G). Co-precipitates mitochondrial Hsp70. Western Blot: 1-2 ug/ml for 2 hrs at RT. Positive control: HeLa or Jurkat cells.
PBS, pH 7.4, 0.09% Sodium Azide, 0.2% BSA
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity.