Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
E. coli (tested or 100% immunogen sequence identity)
Specificity and Use
DNAJA1 / HDJ2 antibody was raised against purified E. coli DnaJ.
Detects a 41kD protein, corresponding to the apparent molecular mass of DnaJ on SDS-PAGE immunoblots, in samples from E. coli. No reactivity is seen with Hsp40 from human, mouse or rat cell lysates on immunoblot analysis.
Western Blot (Colorimetric): 1:5000. Immunoprecipitation: 1:200. Positive control: Recombinant E. coli DnaJ Protein.
DNAJA1 Antibody, DNAJ2 Antibody, HDJ-2 Antibody, HDJ2 Antibody, HSJ2 Antibody, HSPF4 Antibody, Human DnaJ protein 2 Antibody, NEDD7 Antibody, HSDJ Antibody, DJ-2 Antibody, DjA1 Antibody, DnaJ protein homolog 2 Antibody, Heat shock 40 kDa protein 4 Antibody, Heat shock protein J2 Antibody, HSJ-2 Antibody
Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510).