DMRT1

doublesex and mab-3 related transcription factor 1

Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis.

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Products

Antibodies (49)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (49)

Recombinant (2)

Target

DMRT1 (53)

Reactivity

Human (45)

Mouse (7)

Rat (5)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Monkey (3)

Pig (3)

Application

IHC (9)

IHC-P (5)

WB (46)

ELISA (11)

Host

rabbit (33)

mouse (16)

Product Group

IHCPlus (1)

Isotype

IgG (24)

IgG1 (6)

IgG1,k (1)

IgG2a (2)

IgG2b (6)

Clonality

monoclonal mc (15)

polyclonal pc (34)

Clone

1G11 (1)

2H1 (2)

OTI1G10 (2)

OTI2A10 (2)

OTI3G10 (2)

OTI4B5 (2)

OTI4E12 (2)

OTI5D6 (2)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (6)

Carrier-free (7)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (2)

Unconjugated (27)

Epitope

aa1-210 (14)

aa296-322 (7)

C-Terminus (4)

N-Terminus (4)

aa92-141 (4)

aa98-128 (1)

Publications

No (53)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

DMRT1 Antibody (aa98-128) LS-C408137

Antibody:

DMRT1 Rabbit anti-Human Polyclonal (aa98-128) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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DMRT1 Antibody LS-C502226

Antibody:

DMRT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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IHC-plus™ DMRT1 Antibody (aa1-210, clone 2H1) LS-B13041

(4.0) Rating

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (2H1) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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DMRT1 Antibody (aa1-210, clone OTI4E12) LS-C340360

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (OTI4E12) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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DMRT1 Antibody (aa1-210, clone OTI4E12, Carrier-free) LS-C791345

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI4E12) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

DMRT1 Antibody (aa1-210, clone OTI4B5) LS-C340311

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (OTI4B5) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

DMRT1 Antibody (aa1-210, clone OTI4B5, Carrier-free) LS-C791293

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI4B5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

DMRT1 Antibody (clone 1G11) LS-C197063

Antibody:

DMRT1 Mouse anti-Human Monoclonal (1G11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

DMRT1 Antibody LS-C490600

Antibody:

DMRT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

DMRT1 Antibody (aa1-210, clone 2H1, Carrier-free) LS-C798427

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (2H1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

Select

DMRT1 Antibody (aa296-322) LS-C320865

Antibody:

DMRT1 Rabbit anti-Human Polyclonal (aa296-322) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

DMRT1 Antibody (aa296-322, Biotin) LS-C234631

Antibody:

DMRT1 Rabbit anti-Human Polyclonal (aa296-322) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

DMRT1 Antibody (aa296-322, FITC) LS-C234632

Antibody:

DMRT1 Rabbit anti-Human Polyclonal (aa296-322) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

DMRT1 Antibody (aa296-322, Azide-free, HRP) LS-C249840

Antibody:

DMRT1 Rabbit anti-Human Polyclonal (aa296-322) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

DMRT1 Antibody (aa296-322, APC) LS-C234630

Antibody:

DMRT1 Rabbit anti-Human Polyclonal (aa296-322) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DMRT1 Antibody (aa296-322, PE) LS-C234633

Antibody:

DMRT1 Rabbit anti-Human Polyclonal (aa296-322) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

DMRT1 Antibody (C-Terminus) LS-C116066

Antibody:

DMRT1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

DMRT1 Antibody (aa1-210, clone OTI3G10) LS-C340295

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (OTI3G10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

DMRT1 Antibody (aa1-210, clone OTI3G10, Carrier-free) LS-C791276

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI3G10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

DMRT1 Antibody (aa1-210, clone OTI5D6) LS-C340309

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (OTI5D6) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

DMRT1 Antibody (aa1-210, clone OTI5D6, Carrier-free) LS-C799591

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI5D6) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

DMRT1 Antibody (aa1-210, clone OTI1G10) LS-C340305

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (OTI1G10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

DMRT1 Antibody (aa1-210, clone OTI1G10, Carrier-free) LS-C791282

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI1G10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

DMRT1 Antibody (aa1-210, clone OTI2A10) LS-C794062

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (OTI2A10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

DMRT1 Antibody (aa1-210, clone OTI2A10, Carrier-free) LS-C798401

Antibody:

DMRT1 Mouse anti-Human Monoclonal (aa1-210) (Carrier-free) (OTI2A10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Viewing 1-25 of 53 product results

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