Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
DMPK Antibody, DM-kinase Antibody, DM1 Antibody, DM1PK Antibody, DM protein kinase Antibody, DM1 protein kinase Antibody, DMK Antibody, MDPK Antibody, Myotonic dystrophy kinase Antibody, MT-PK Antibody, Myotonin kinase Antibody, MtPK Antibody, Myotonic protein kinase Antibody, Myotonin protein kinase A Antibody, Thymopoietin homolog Antibody, DM Antibody, Myotonin-protein kinase Antibody
Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation.
Western Blot analysis of DMPK expression in transfected 293T cell line by DMPK monoclonal antibody (M01), clone 2F7.Lane 1: DMPK transfected lysate(69.4 KDa).Lane 2: Non-transfected lysate.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged DMPK is approximately 0.03 ng/ml as a capture antibody.
Western blot analysis of DMPK over-expressed 293 cell line, cotransfected with DMPK Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with DMPK monoclonal antibody (M01) clone 2F7 . GAPDH ( 36.1 kDa ) used as specificity and loading control.