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Anti-DMPK / DM Antibody (clone 2F7) LS-C197062

Ordering

Wt. Vol. Conc. Price
100 µg - - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DMPK / DM Antibodies

Anti-DMPK / DM Antibody (aa323-372) IHC-plus™ LS-B5734
Rabbit Polyclonal (IgG) to Human DMPK / DM
Human, Mouse, Bat, Bovine, Dog, Guinea pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-DMPK / DM Antibody (aa11-39) LS-C167452
Rabbit Polyclonal to Human DMPK / DM
Human
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 2F7] (IgG2a,k) to Human DMPK / DM
Human
Western blot, ELISA, RNA interference
Unconjugated

Details

Human DMPK / DM
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [2F7]
Unconjugated
Protein A purified
Unmodified

Applications

  • Western blot
  • ELISA
  • RNA interference

Specificity and Use

DMPK / DM antibody was raised against dMPK (AAH62553, aa303-420 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Human DMPK / DM
RNAi Knockdown: Antibody validated. Sandwich ELISA: Recombinant protein. Western Blot: Transfected lysate, Recombinant protein.

Packaging

PBS, pH 7.2
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
For research use only.

About DMPK / DM

Q09013 NM_004409 NP_004400.4

DMPK Antibody, DM-kinase Antibody, DM1 Antibody, DM1PK Antibody, DM protein kinase Antibody, DM1 protein kinase Antibody, DMK Antibody, MDPK Antibody, Myotonic dystrophy kinase Antibody, MT-PK Antibody, Myotonin kinase Antibody, MtPK Antibody, Myotonic protein kinase Antibody, Myotonin protein kinase A Antibody, Thymopoietin homolog Antibody, DM Antibody, Myotonin-protein kinase Antibody

Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation.

Western blot

Western blot
Western Blot analysis of DMPK expression in transfected 293T cell line by DMPK monoclonal antibody (M01), clone 2F7.Lane 1: DMPK transfected lysate(69.4 KDa).Lane 2: Non-transfected lysate.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged DMPK is approximately 0.03 ng/ml as a capture antibody.

RNA interference

RNA interference
Western blot analysis of DMPK over-expressed 293 cell line, cotransfected with DMPK Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with DMPK monoclonal antibody (M01) clone 2F7 . GAPDH ( 36.1 kDa ) used as specificity and loading control.
 

Requested From: United States
Date Requested: 12/7/2016

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