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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DMD / Dystrophin Antibody (C‑Terminus) LS‑C22980
Note: This antibody replaces LS-C65095
Antibody
Dystrophin antibody LS-C22980 is an unconjugated rabbit polyclonal antibody to Dystrophin (DMD) from human and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C22980-250
250 µl
Unavailable

Popular DMD / Dystrophin Products

Human skeletal muscle stained with Anti-Dystrophin antibody
Species: Human, Mouse
Applications: IHC, Western blot
Antibody
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Applications: IHC, IHC - Frozen, Immunofluorescence, ELISA
Anti-Dystrophin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8434 dilution 5 ug/ml.
Species: Human, Mouse, Rat
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Anti-Dystrophin antibody IHC of human skeletal muscle, membrane. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8653 dilution 10 ug/ml.
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Western blot of recombinant DMD / Dystrophin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: IHC, Western blot

Product Description

Dystrophin antibody LS-C22980 is an unconjugated rabbit polyclonal antibody to Dystrophin (DMD) from human and rat. Validated for IHC and WB.
About DMD / Dystrophin
The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. P11532 NM_000109 P11532

DMD Antibody, BMD Antibody, CMD3B Antibody, DXS206 Antibody, Dystrophin Antibody, DXS230 Antibody, DXS239 Antibody, DXS269 Antibody, DXS142 Antibody, DXS268 Antibody, DXS164 Antibody, DXS270 Antibody, DXS272 Antibody


Specifications

Target
Human DMD / Dystrophin
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
A synthetic peptide corresponding to C-terminal of human Dystrophin. Molecular weight of antigen: 427kD Epitope: C-terminal Cellular Localization: Cell membrane.
Epitope
C-Terminus
Specificity
Recognizes human Dystrophin. Species cross-reactivity: rat.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Immunohistochemistry (Formalin/paraffin): 1:50 to 1:100 for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 8.0 for 10-20 min followed by cooling at RT for 20 min. Positive control: Skeletal muscle.
Presentation
10 mM PBS, pH 7.6, 0.2% BSA, 15 mM sodium azide, 40% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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