DMAP1

DNA methyltransferase 1 associated protein 1

Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity.

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Products

Antibodies (21)

Proteins (8)

Type

Over-Expression Lysate (6)

Primary (21)

Recombinant (2)

Target

DMAP1 (29)

Reactivity

Human (21)

Mouse (12)

Rat (9)

Bat (9)

Bovine (9)

Chicken (3)

Chimpanzee (9)

Dog (9)

Gibbon (9)

Guinea pig (9)

Hamster (9)

Horse (6)

Monkey (9)

Pig (3)

Rabbit (9)

Xenopus (3)

Zebrafish (6)

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Application

IHC (5)

IHC-P (1)

WB (21)

ELISA (2)

Peptide-ELISA (1)

Host

rabbit (17)

mouse (2)

goat (2)

Isotype

IgG (18)

IgG1 (1)

IgG1,k (1)

Clonality

monoclonal mc (2)

polyclonal pc (19)

Clone

2G12 (1)

Format

AP Conjugated (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (11)

Epitope

C-Terminus (4)

N-Terminus (4)

aa150-199 (4)

aa400-450 (1)

aa50-100 (1)

Publications

No (29)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (7)

Species

Human (5)

Source

293T Cells (3)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Select

DMAP1 Antibody (clone 2G12) LS-C134088

Antibody:

DMAP1 Mouse anti-Human Monoclonal (2G12) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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DMAP1 Antibody LS-C751611

Antibody:

DMAP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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DMAP1 Antibody (AP) LS-C408414

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (AP) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

AP Conjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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DMAP1 Antibody LS-C802762

Antibody:

DMAP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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DMAP1 Antibody LS-C766105

Antibody:

DMAP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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DMAP1 Antibody LS-C64921

Antibody:

DMAP1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

Select

DMAP1 Antibody (aa150-199) LS-C31654

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (aa150-199) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

DMAP1 Antibody (aa150-199, HRP) LS-C428746

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (aa150-199) (HRP) Antibody

Reactivity:

Chicken, Zebrafish, Horse, Bat, Hamster, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

DMAP1 Antibody (aa150-199, Biotin) LS-C428210

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (aa150-199) (Biotin) Antibody

Reactivity:

Chicken, Zebrafish, Horse, Bat, Hamster, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

DMAP1 Antibody (aa150-199, FITC) LS-C428743

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (aa150-199) (FITC) Antibody

Reactivity:

Chicken, Zebrafish, Horse, Bat, Hamster, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DMAP1 Antibody (C-Terminus) LS-C31116

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

DMAP1 Antibody (C-Terminus, HRP) LS-C438458

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

DMAP1 Antibody (C-Terminus, Biotin) LS-C438456

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

DMAP1 Antibody (C-Terminus, FITC) LS-C438457

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DMAP1 Antibody (N-Terminus) LS-C31117

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

DMAP1 Antibody (N-Terminus, HRP) LS-C438455

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

DMAP1 Antibody (N-Terminus, Biotin) LS-C438453

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

DMAP1 Antibody (N-Terminus, FITC) LS-C438454

Antibody:

DMAP1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DMAP1 Antibody LS-C668858

Antibody:

DMAP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

DMAP1 Antibody (aa50-100) LS-C287133

Antibody:

DMAP1 Goat anti-Human Polyclonal (aa50-100) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

DMAP1 Antibody (aa400-450) LS-C287134

Antibody:

DMAP1 Goat anti-Human Polyclonal (aa400-450) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

Human DMAP1 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G62784

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91421

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

20 µg/$150

Select

Human DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91424

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

20 µg/$215

Select

Human DMAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91423

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.8 kDa

Price:

20 µg/$150

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