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Anti-DLL4 Antibody (aa550-600) LS-C148713

Catalog	Size	Price
LS-C148713-100	100 µg (0.5 mg/ml)	Unavailable

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Antibody:	Rabbit Polyclonal to Human DLL4
Reactivity:	Human
Application:	IHC - Paraffin, Western blot, ELISA
Format:	Unconjugated

Anti-DLL4 Antibody (aa27-525, Biotin) LS-C125452

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Anti-DLL4 Antibody (aa550-600) LS-C148713

Antibody:	Rabbit Polyclonal to Human DLL4
Reactivity:	Human, Mouse
Application:	Western blot
Format:	Unconjugated

Anti-DLL4 Antibody (clone 4A11) LS-C169100

Antibody:	Mouse Monoclonal [clone 4A11] (IgG1) to Human DLL4
Reactivity:	Human
Application:	IHC - Paraffin, Western blot, ELISA
Format:	Unconjugated

Anti-DLL4 Antibody (aa146-195) IHC-plus™ LS-B10026

Antibody:	Rabbit Polyclonal (IgG) to Human DLL4
Reactivity:	Human, Monkey, Mouse, Rat, Dog
Application:	IHC - Frozen, Western blot
Format:	Unconjugated

Antibody:	Rabbit Polyclonal to Human DLL4
Reactivity:	Human, Mouse
Application:	Western blot
Format:	Unconjugated

Details

Target:	Human DLL4
Host:	Rabbit
Reactivity:	Human, Mouse (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Protein A purified
Modifications:	Unmodified

Applications

Approved:

Western blot (3 - 6 µg/ml)

Failed:

IHC - Paraffin

Specificity and Use

Immunogen:	DLL4 antibody was raised against a portion of amino acids 550-600 of human DLL4.
Epitope:	aa550-600
Specificity:	Human DLL4.

Packaging

Presentation:	PBS, 0.05% BSA, 0.05% sodium azide
Storage:	Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
Restrictions:	For research use only.

About DLL4

Uniprot: Q9NR61 NCBI: NM_019074 NP_061947.1

Synonyms: DLL4 Antibody, Delta-like 4 protein Antibody, Delta like 4 Antibody, Delta-like 4 (Drosophila) Antibody, Delta-like 4 homolog Antibody, Drosophila Delta homolog 4 Antibody, Notch ligand DLL4 Antibody, Delta 4 Antibody, Delta ligand 4 Antibody, Delta-like protein 4 Antibody, Delta4 Antibody, Hdelta2 Antibody, Notch ligand delta-2 Antibody

Description: Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

(More About DLL4)

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Technical Help Review

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Western blot

Western blot of DLL4 in HUVEC cell lysate using 1) preimmune sera at 1:5000 and 2) LS-C148713 at 3 ug/ml, and 3) mouse embryo body lysate at 6 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Requested From:
Date Requested: 6/28/2017

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