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Anti-DLG4 / PSD95 Antibody (C-Terminus) IHC-plus™ LS-B3153

Note: This antibody replaces LS-C38646
Catalog Size Price
LS-B3153-50 50 µg (0.25 mg/ml) Unavailable

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Anti-DLG4 / PSD95 Antibody (C-Terminus) IHC-plus™ LS-B3153
Rabbit Polyclonal (IgG) to Human DLG4 / PSD95
Human, Mouse, Rat
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated
Anti-DLG4 / PSD95 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.
Anti-DLG4 / PSD95 Antibody (aa667-679) LS-C112844
Goat Polyclonal to Human DLG4 / PSD95
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Unconjugated
DLG4 antibody (1 ug/ml) staining of Mouse Brain lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Anti-DLG4 / PSD95 Antibody LS-C131534
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Anti-DLG4 / PSD95 Antibody (aa683-732) IHC-plus™ LS-B8203
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IHC, IHC - Paraffin, Western blot
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Anti-PSD95 antibody IHC of human colon, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8203 dilution 2.5-5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

100% Guaranteed
Rabbit Polyclonal (IgG) to Human DLG4 / PSD95
Human, Mouse, Rat
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA (applications tested for the base form of this product only)
Unconjugated

Details

Human DLG4 / PSD95
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (0.5 - 1 µg/ml)
  • Western blot (1 µg/ml)
  • Immunoprecipitation
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

DLG4 / PSD95 antibody was raised against synthetic peptide derived from the C-terminal region of human PSD-95 (KLH).
C-Terminus
Recognizes the ~95kD PSD-95 protein. Cross-reactivity with an unknown protein at ~50kD with rat brain homogenates but not with mouse brain homogenates. Species cross-reactivity: human, rat and mouse.
Immunohistochemistry: LS-B3153 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3153 was determined to be 5 ug/ml.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
4°C or -20°C, Avoid freeze-thaw cycles.
For research use only.

About DLG4 / PSD95

P78352 NM_001365 NP_001356.1

DLG4 Antibody, Disks large homolog 4 Antibody, Presynaptic density protein 95 Antibody, PSD95 Antibody, SAP-90 Antibody, Synapse-associated protein 90 Antibody, PSD-95 Antibody, SAP90 Antibody, Tax interaction protein 15 Antibody, Discs large homolog 4 Antibody

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.

Immunohistochemistry

Anti-DLG4 / PSD95 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.
Anti-DLG4 / PSD95 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.

Immunohistochemistry

Anti-DLG4 / PSD95 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.
Anti-DLG4 / PSD95 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.

Immunohistochemistry

Anti-DLG4 / PSD95 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.
Anti-DLG4 / PSD95 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.

Immunohistochemistry

Anti-DLG4 / PSD95 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.
Anti-DLG4 / PSD95 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3153 concentration 5 ug/ml.

Requested From: 
Date Requested: 5/20/2018

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