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Anti-DLG4 / PSD95 Antibody (aa683-732) IHC-plus™ LS-B8203

Note: This antibody replaces LS-C111304
Catalog Size Price
LS-B8203-50 50 µg (1 mg/ml) Unavailable

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Anti-DLG4 / PSD95 Antibody (aa683-732) IHC-plus™ LS-B8203
Rabbit Polyclonal to Human DLG4 / PSD95
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal to Human DLG4 / PSD95
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit, Zebrafish
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human DLG4 / PSD95
Rabbit
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit, Zebrafish (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (2.5 - 5 µg/ml)
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

DLG4 / PSD95 antibody was raised against synthetic peptide located between aa683-732 of human DLG4 (P78352, NP_001356). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Rabbit, Horse, Guinea pig (100%); Opossum (92%).
LS-E18429 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B8203. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa683-732
Human DLG4 / PSD95
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About DLG4 / PSD95

P78352 NM_001365 NP_001356.1

DLG4 Antibody, Disks large homolog 4 Antibody, Presynaptic density protein 95 Antibody, PSD95 Antibody, SAP-90 Antibody, Synapse-associated protein 90 Antibody, PSD-95 Antibody, SAP90 Antibody, Tax interaction protein 15 Antibody, Discs large homolog 4 Antibody

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.

Immunohistochemistry

Immunohistochemistry
Anti-PSD95 antibody IHC of human colon, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8203 dilution 2.5-5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
DLG4 / PSD95 antibody LS-B8203 Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 6/24/2017

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