Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
DLG3 / SAP102 antibody was raised against synthetic peptide: G(83)PVPPKPVPGKNTPKLNG(100). Immunizing peptide corresponds to amino acid residues 83-100 of rat SAP 102. Percent identity by BLAST analysis: Rat (100%); Human, Gorilla, Monkey, Marmoset, Mouse, Hamster, Panda, Porcine, Bovine, Dog, Rabbit (94%); Elephant, Bat (88%).
Species cross-reactivity: Cross-reacts with Rat. Does not cross-react with Mouse (see review).
Suitable for use in Western Blot and Immunohistochemistry (Fr).
PBS, 1 mg/ml BSA, 0.05% sodium azide
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
DLG3 / SAP102 is a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described.