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Anti-DKK4 Antibody (aa162-189) LS-C167429

Ordering

Wt. Vol. Conc. Price
- 400 µl - Unavailable

Most Popular DKK4 Antibodies

Anti-DKK4 Antibody (aa188-217) LS-C98298
Rabbit Polyclonal to Human DKK4
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-DKK4 Antibody (aa1-30) IHC-plus™ LS-B7774
Rabbit Polyclonal to Human DKK4
Human
IHC - Paraffin, Western blot
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Immunohistochemistry Image
Anti-DKK4 Antibody (aa19-224) LS-C379929
Rabbit Polyclonal (IgG) to Human DKK4
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human DKK4
Human
Western blot
Unconjugated

Details

Human DKK4
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

LS-E1126 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C167429. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa162-189
This DKK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from the C-terminal region of human DKK4.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About DKK4

Q9UBT3 NM_014420 NP_055235.1

DKK4 Antibody, Dickkopf-4 Antibody, DKK-4 Antibody, Dickkopf-related protein 4 Antibody, HDkk-4 Antibody

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Western blot

Western blot
Western blot of lysates from Jurkat, HUVEC cell line (from left to right), using DKK4 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
 

Requested From: 
Date Requested: 3/28/2017

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