DKK3

Dickkopf WNT Signaling Pathway Inhibitor 3

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

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Products

Antibodies (73)

ELISA Kits (16)

Proteins (16)

Type

Custom (2)

Development Kit (2)

Over-Expression Lysate (6)

Primary (73)

Recombinant (10)

Sandwich (12)

Target

DKK3 (105)

Reactivity

Human (60)

Mouse (28)

Rat (16)

Bat (3)

Chicken (1)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (5)

Non-Human Primate (1)

Orangutan (3)

Pig (3)

Rabbit (3)

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Application

IHC (22)

IHC-P (9)

WB (55)

Flo (6)

ELISA (34)

IF (1)

Peptide-ELISA (3)

Host

rabbit (63)

mouse (9)

goat (1)

Product Group

DevKit DuoPlus (2)

IHCPlus (3)

Isotype

IgG (32)

IgG1 (6)

IgG1,k (1)

IgG2a (1)

Clonality

monoclonal mc (10)

polyclonal pc (63)

Clone

019 (1)

05 (1)

4G7 (2)

8A5C6 (2)

8D5A3E3 (1)

AT103B5 (1)

Format

96-Well Microplate (4)

96-Well Strip Plate (10)

Antibody Pair and Standard (2)

APC (3)

APC Conjugated (5)

Azide-free (2)

Biotin Conjugated (7)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (5)

Preservative Free (8)

Unconjugated (36)

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Epitope

aa22-350 (8)

aa23-349 (8)

aa41-348 (8)

aa15-45 (7)

C-Terminus (6)

aa51-100 (4)

80-160 aa, Internal (1)

Amino Acid: 91-350 (1)

aa340-350 (1)

aa58-87 (1)

aa98-147 (1)

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Publications

No (104)

Yes (1)

Sample Type

Cell Culture Supernatants (6)

Cell Lysates (4)

Cell Supernatant (1)

Plasma (14)

Serum (14)

Tissue Homogenates (7)

Tag

6His, C-terminus (2)

GST (1)

His (2)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (7)

Species

Human (10)

Mouse (2)

Rat (1)

Source

293T Cells (3)

CHO Cells (1)

E. coli (4)

HEK 293 Cells (4)

Human Cells (2)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (3)

Biologically Active

Biologically active (1)

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IHC-plus™ DKK3 Antibody (aa340-350) LS-B4434

(4.0) Rating

Antibody:

DKK3 Goat anti-Human Polyclonal (aa340-350) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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DKK3 Antibody (aa15-45) LS-C98295

(4.0) Rating

(1) Publication(s)

Antibody:

DKK3 Rabbit anti-Human Polyclonal (aa15-45) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Rat DKK3 (Sandwich ELISA) ELISA Kit - LS-F23625

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse DKK3 (Sandwich ELISA) ELISA Kit - LS-F25421

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$854

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Human DKK3 (Sandwich ELISA) ELISA Kit - LS-F65

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

2.743 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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DKK3 Antibody (clone 8A5C6) LS-C169148

Antibody:

DKK3 Mouse anti-Human Monoclonal (8A5C6) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

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Human DKK3 Protein (Recombinant 6His, C-terminus) (Ala22-Ile350) - LS-G38926

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

37.22kD

Price:

10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157

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DKK3 Antibody LS-C403960

Antibody:

DKK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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DKK3 Antibody (clone 4G7) LS-C108794

Antibody:

DKK3 Mouse anti-Human Monoclonal (4G7) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µl/$435

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Human DKK3 (Sandwich ELISA) ELISA Kit - LS-F2977

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$795

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IHC-plus™ DKK3 Antibody LS-B10864

(4.0) Rating

Antibody:

DKK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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DKK3 Antibody (Preservative Free) LS-C818509

Antibody:

DKK3 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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DKK3 Antibody (clone 019, Preservative Free) LS-C819290

Antibody:

DKK3 Rabbit anti-Mouse Monoclonal (Preservative Free) (019) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

20 µl/$271; 100 µl/$412

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DKK3 Antibody (aa51-100) LS-C146493

Antibody:

DKK3 Rabbit anti-Human Polyclonal (aa51-100) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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DKK3 Antibody LS-C665102

Antibody:

DKK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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IHC-plus™ DKK3 Antibody LS-B13378

(4.0) Rating

Antibody:

DKK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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DKK3 Antibody LS-C834116

Antibody:

DKK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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DKK3 Antibody (Amino Acid: 91-350, clone 8A5C6) LS-C759626

Antibody:

DKK3 Mouse anti-Human Monoclonal (Amino Acid: 91-350) (8A5C6) Antibody

Reactivity:

Human

Applications:

Flo, IHC, WB

Format:

Unconjugated

Price:

100 µg/$503

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Mouse DKK3 (Sandwich ELISA) ELISA Kit - LS-F23053

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat DKK3 Protein (Recombinant His, N-Terminal) (aa41-348) - LS-G25289

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

38.2 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human DKK3 Protein (Recombinant His) - LS-G1885

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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DKK3 Antibody (aa15-45) LS-C327197

Antibody:

DKK3 Rabbit anti-Human Polyclonal (aa15-45) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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DKK3 Antibody (aa15-45, Azide-free, HRP) LS-C247535

Antibody:

DKK3 Rabbit anti-Human Polyclonal (aa15-45) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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DKK3 Antibody (aa15-45, APC) LS-C244156

Antibody:

DKK3 Rabbit anti-Human Polyclonal (aa15-45) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP, Azide-free
• APC

• Unconjugated
• HRP, Azide-free
• APC

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DKK3 Antibody LS-C812567

Antibody:

DKK3 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human, Monkey

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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