LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
DKK3 Antibody (aa51‑100) LS‑C146493
DKK3 antibody LS-C146493 is an unconjugated rabbit polyclonal antibody to DKK3 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C146493-50
50 µg
Unavailable

Popular DKK3 Products

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with DKK3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Western blot using DKK3 mouse monoclonal antibody against HEK293 (1), MCF-7 (2) and HL7702 (3) cell lysate.
Species: Human
Applications: Flow Cytometry, ELISA
Anti-DKK3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4434 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
IHC of paraffin-embedded brain tissues using DKK3 mouse monoclonal antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Flow Cytometry, ELISA
Anti-DKK3 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10864 concentration 7.5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

DKK3 antibody LS-C146493 is an unconjugated rabbit polyclonal antibody to DKK3 from human, mouse, rat and other species. Validated for WB.
About DKK3
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Q9UBP4 NM_013253 NP_037385.2

DKK3 Antibody, Dickkopf-3 Antibody, Dkk-3 Antibody, Dickkopf homolog 3 Antibody, Dickkopf-related protein 3 Antibody, HDkk-3 Antibody, Regulated in glioma Antibody, RIG-like 7-1 Antibody, REIC Antibody, RIG-like 5-6 Antibody


Specifications

Target
Human DKK3
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Guinea pig, Hamster, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
DKK3 antibody was raised against synthetic peptide located between aa51-100 of human DKK3 (Q9UBP4, NP_056965). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Bat, Rabbit, Horse, Pig, Guinea pig (100%); Bovine, Opossum (92%); Zebra finch, Chicken (85%).
Blocking Peptide
LS-E23230 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C146493. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa51-100
Specificity
Human DKK3
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Western blot

DKK3 antibody LS-C146493 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
DKK3 antibody LS-C146493 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

DKK3 antibody LS-C146493 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
DKK3 antibody LS-C146493 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

DKK3 antibody LS-C146493 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
DKK3 antibody LS-C146493 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

DKK3 antibody LS-C146493 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
DKK3 antibody LS-C146493 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/20/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number