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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DKK2 Antibody (aa225‑251) LS‑C98294 Best Seller
DKK2 antibody LS-C98294 is an unconjugated rabbit polyclonal antibody to human DKK2. Validated for IHC and WB.
Catalog
Size
Price
LS-C98294-400
400 µl
Unavailable

Popular DKK2 Products

Anti-DKK2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8226 dilution 2.5-5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Monkey, Rat, Bat, Dog, Guinea pig, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot

Product Description

DKK2 antibody LS-C98294 is an unconjugated rabbit polyclonal antibody to human DKK2. Validated for IHC and WB.
About DKK2
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Q9UBU2 NM_014421 NP_055236.1

DKK2 Antibody, DKK-2 Antibody, Dickkopf homolog 2 Antibody, Dickkopf related protein-2 Antibody, HDkk-2 Antibody, Dickkopf-2 Antibody, Dickkopf-related protein 2 Antibody


Specifications

Target
Human DKK2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E3795 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C98294. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa225-251
Specificity
This DKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-251 amino acids from the C-terminal region of human DKK2.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Customer Reviews (0)


Images


Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

DKK2 Antibody (C239) western blot of 293 cell line lysates (35 ug/lane). The DKK2 antibody detected the DKK2 protein (arrow).
DKK2 Antibody (C239) western blot of 293 cell line lysates (35 ug/lane). The DKK2 antibody detected the DKK2 protein (arrow).

Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

DKK2 Antibody (C239) western blot of 293 cell line lysates (35 ug/lane). The DKK2 antibody detected the DKK2 protein (arrow).
DKK2 Antibody (C239) western blot of 293 cell line lysates (35 ug/lane). The DKK2 antibody detected the DKK2 protein (arrow).

Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

DKK2 Antibody (C239) western blot of 293 cell line lysates (35 ug/lane). The DKK2 antibody detected the DKK2 protein (arrow).
DKK2 Antibody (C239) western blot of 293 cell line lysates (35 ug/lane). The DKK2 antibody detected the DKK2 protein (arrow).

Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

DKK2 Antibody (C239) western blot of 293 cell line lysates (35 ug/lane). The DKK2 antibody detected the DKK2 protein (arrow).
DKK2 Antibody (C239) western blot of 293 cell line lysates (35 ug/lane). The DKK2 antibody detected the DKK2 protein (arrow).


Requested From: 
Date Requested: 6/24/2018

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