Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
DKK1 antibody was raised against nS0-derived, recombinant rat Dkk-1.
Recognizes rat Dkk-1.
Suitable for use in Direct ELISA and Western Blot. Direct ELISA: 0.5-1 ug/mL detection limit for rrDkk-1 ~0.2 ng/well. Western Blot: 0.1-0.2 ug/mL detection limit for rrDkk-1 ~10 ng/lane under non-reducing and reducing conditions.
Lyophilized from PBS, 5% trehalose. Reconstitute, 200 ul 40-50% glycerol, PBS.
1,000 µl Sterile PBS
Store at -20°C lyophilized. Once reconstituted, aliquot and store at -20°C.
DKK1 Antibody, Dickkopf-1 like Antibody, DKK-1 Antibody, Dickkopf-1 Antibody, Dickkopf-related protein 1 Antibody, Dickkopf related protein-1 Antibody, HDkk-1 Antibody, Hdkk1 Antibody, Dickkopf-like protein 1 Antibody, SK Antibody
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.