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Anti-DKK1 Antibody (aa30-272, clone 259631) LS-C150181


Wt. Vol. Conc. Price
100 µg - - Unavailable

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Rat Monoclonal [clone 259631] (IgG2b) to Mouse DKK1
IHC, Western blot


Mouse DKK1
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [259631]
Protein A/G purified


  • IHC (8 - 25 µg/ml)
  • Western blot (1 µg/ml)

Specificity and Use

DKK1 antibody was raised against mouse myeloma cell line NS0-derived recombinant mouse Dkk1 Ser30-His272 Accession # O54908.
Detects mouse Dkk1 in direct ELISAs and Western blots. Does not cross-react with recombinant human Dkk1, 3, or4.
Western Blot, 1 µg/ml, Recombinant Mouse Dkk-1. Recombinant Mouse Dkk-1. Immunohistochemistry, 8-25 µg/ml.


Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 200 ul
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About DKK1

O94907 NM_012242 NP_036374.1

DKK1 Antibody, Dickkopf-1 like Antibody, DKK-1 Antibody, Dickkopf-1 Antibody, Dickkopf-related protein 1 Antibody, Dickkopf related protein-1 Antibody, HDkk-1 Antibody, Hdkk1 Antibody, Dickkopf-like protein 1 Antibody, SK Antibody

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.


Dkk-1 in Mouse Embryo. Dkk-1 was detected in immersion fixed frozen sections of mouse embryo (15 d. p. c) using Mouse Dkk-1 Monoclonal Antibody at 25 ug/ml overnight at 4°C. Tissue was stained using Anti-Rat HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of epithelial cells in lung.

Requested From: 
Date Requested: 4/26/2017

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