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Anti-DKK1 Antibody (aa250-262) IHC-plus™ LS-B194

Note: This antibody replaces LS-C20153, LS-C64743


Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular DKK1 Antibodies

Anti-DKK1 Antibody (Cytoplasmic Domain) IHC-plus™ LS-A2867
Rabbit Polyclonal to Human DKK1
IHC - Paraffin
Immunohistochemistry Image
Anti-DKK1 Antibody (aa250-262) IHC-plus™ LS-B194
Goat Polyclonal to Human DKK1
Human, Monkey, Mouse, Bovine, Dog, Goat, Horse, Pig
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human DKK1
Human, Monkey, Mouse, Bovine, Dog, Goat, Horse, Pig
IHC - Paraffin, Western blot, ELISA


Human DKK1
Human, Monkey, Mouse, Bovine, Dog, Goat, Horse, Pig (tested or 100% immunogen sequence identity)
Rat, Bat, Hamster (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (10 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • ELISA (1:128000)

Specificity and Use

DKK1 antibody was raised against synthetic peptide C-DHHQASNSSRLHT from the C-terminus of human DKK1 (NP_036374.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Bovine, Dog, Goat, Elephant, Panda, Horse, Pig (100%); Gibbon, Rat, Bat, Hamster, Platypus (92%); Rabbit (85%).
LS-E25759 - Lyophilized - 100 µg - $145.00
Human DKK1.
Immunohistochemistry: LS-B194 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B194 was determined to be 10 ug/ml.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About DKK1

O94907 NM_012242 NP_036374.1

DKK1 Antibody, Dickkopf-1 like Antibody, DKK-1 Antibody, Dickkopf-1 Antibody, Dickkopf-related protein 1 Antibody, Dickkopf related protein-1 Antibody, HDkk-1 Antibody, Hdkk1 Antibody, Dickkopf-like protein 1 Antibody, SK Antibody

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.


Anti-DKK1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B194 concentration 10 ug/ml.

Requested From: United States
Date Requested: 10/25/2016

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