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| Catalog Number | Size | Price |
|---|---|---|
| LS-C56896-0.1 | 0.1 mg (1 mg/ml) | $518 |
Polyclonal Rabbit anti‑Human DISC1 Antibody (IHC, WB) LS‑C56896
Polyclonal Rabbit anti‑Human DISC1 Antibody (IHC, WB) LS‑C56896
Antibody:
DISC1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
DISC1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
DISC1 antibody LS-C56896 is an unconjugated rabbit polyclonal antibody to human DISC1. Validated for IHC and WB.
Target
Human DISC1
Synonyms
DISC1 | C1orf136 | Disrupted in schizophrenia 1 | KIAA0457 | SCZD9
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
An 18 amino acid peptide located near the centre of human DISC1.
Specificity
Recognizes disrupted in schizophrenia 1 (DISC1), ~93 kD protein located in the nucleus, cytoplasm and mitochondria. The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1;11) (q42.1;q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition. Has been found suitable for immunocytochemistry (ICC) at a concentration of 5 ug/ml.
Applications
- IHC - Frozen
- Western blot (1 - 2 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot: LS-C56896 detects bands of approximately 95-100kD in SK-N-SH cell lysate.
Presentation
PBS, 0.02% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About DISC1
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Mouse, Human
Applications:
IHC, IHC - Paraffin, Western blot
Reactivity:
Human
Range:
40-10000 pg/ml
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Reactivity:
Human
Range:
3.12-200 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
