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Anti-DIS / CCAR1 Antibody (aa901-912) LS-C108942

Ordering

Wt. Vol. Conc. Price
100 µg - - Unavailable

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Most Popular DIS / CCAR1 Antibodies

Anti-DIS / CCAR1 Antibody (aa1-50) LS-C286363
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IHC - Paraffin, Immunofluorescence
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Anti-DIS / CCAR1 Antibody (aa1-50) LS-C287327
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Anti-DIS / CCAR1 Antibody LS-C335654
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100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human DIS / CCAR1
Human, Monkey, Rat, Bat, Bovine, Dog, Hamster, Pig
Western blot, ELISA
Unconjugated

Details

Human DIS / CCAR1
Goat
Human, Monkey, Rat, Bat, Bovine, Dog, Hamster, Pig (tested or 100% immunogen sequence identity)
Horse (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1 - 3 µg/ml)
  • ELISA

  • IHC - Paraffin

Specificity and Use

DIS / CCAR1 antibody was raised against synthetic peptide RYCKERPSKDKE from an internal region (near C-terminus) of human CCAR1 (NP_060707.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Hamster, Elephant, Panda, Dog, Bat, Bovine, Pig (100%); Rat, Horse (92%); Mouse, Rabbit, Opossum, Xenopus (83%).
LS-E27242 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C108942. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa901-912
Human CCAR1.
Western Blot: Approx 120kD band observed in Mouse and Rat Skeletal Muscle lysates (calculated MW of 132kD according to Mouse NP_080477.1 and Rat NP_001102005.1). Recommended concentration: 1-3 ug/ml. An additional band of unknown identity was also consistently observed at 33kD. This band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About DIS / CCAR1

Q8IX12 NP_060707.2

CCAR1 Antibody, CARP1 Antibody, CARP-1 Antibody, Death inducer with SAP domain Antibody, DIS Antibody, RP11-437A18.1 Antibody

Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation By similarity.

Western blot

Western blot
CCAR1 antibody (1 ug/ml) staining of Rat Skeletal Muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
 

Requested From: 
Date Requested: 3/30/2017

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