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Anti-DIS / CCAR1 Antibody (aa700-750) LS-C188044

Catalog Size Price
LS-C188044-100 100 µg (1 mg/ml) Unavailable

Related Products

9 DIS / CCAR1 Antibodies

Most Popular DIS / CCAR1 Antibodies

Anti-DIS / CCAR1 Antibody (aa1-50) LS-C286363
Rabbit Polyclonal (IgG) to Human DIS / CCAR1
Human, Mouse, Rat, Bovine, Dog, Horse, Rabbit, Chicken
IHC, IHC - Paraffin, Immunofluorescence
Unconjugated
Detection of Mouse CCAR1 by Immunohistochemistry. Sample: FFPE section of mouse squamous cell carcinoma. Antibody: Affinity purified rabbit anti-CCAR1 used at a dilution of 1:250. Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1:100.
Anti-DIS / CCAR1 Antibody (aa1-50) LS-C287327
Rabbit Polyclonal (IgG) to Human DIS / CCAR1
Human, Mouse, Rat, Bovine, Dog, Horse, Rabbit, Chicken
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Detection of Human and Mouse CCAR1 by Immunohistochemistry. Sample: FFPE section of human stomach carcinoma (left) and mouse renal cell carcinoma (right). Antibody: Affinity purified rabbit anti-CCAR1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Anti-DIS / CCAR1 Antibody LS-C335654
Rabbit Polyclonal (IgG) to Human DIS / CCAR1
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Immunofluorescence analysis of HeLa cells.
Anti-DIS / CCAR1 Antibody (aa1-200) LS-C378111
Rabbit Polyclonal (IgG) to Human DIS / CCAR1
Human
IHC, IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Anti-DIS / CCAR1 Antibody LS-C404899
Rabbit Polyclonal (IgG) to Human DIS / CCAR1
Human, Mouse
IHC, ELISA
Unconjugated
Immunohistochemistry of Human liver cancer using CCAR1 Polyclonal Antibody at dilution of 1:40.

100% Guaranteed
Rabbit Polyclonal (IgG) to Human DIS / CCAR1
Human
Western blot, Immunoprecipitation
Unconjugated

Details

Human DIS / CCAR1
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • Western blot (1:2000 - 1:10000)
  • Immunoprecipitation

Specificity and Use

DIS / CCAR1 antibody was raised against synthetic peptide corresponding to an epitope within amino acid residues 700-750 of human CCAR1(NP_060707.2).
aa700-750
Recognizes human CCAR1 (Cell cycle and apoptosis regulatory protein 1), a perinuclear phosphoprotein expressed by several epithelial cancer cell lines, which has been implicated as a regulator of transcription, through association with components of the Mediator and p160 coactivator complexes, and its role as a p53 coactivator. CCAR1 acts as an inducer of apoptosis signalling, under the regulation of the epidermal growth factor receptor (EGFR), caspase-9 activation, the mitogen-activated protein kinase pathway, and in response to chemotherapeutic agents, and has been shown to act as a suppressor of human breast cancer growth.

Packaging

Tris-citrate/PBS, 0.1% sodium azide
4°C or -20°C, Avoid freeze-thaw cycles.
For research use only.

About DIS / CCAR1

Q8IX12 NP_060707.2

CCAR1 Antibody, CARP1 Antibody, CARP-1 Antibody, Death inducer with SAP domain Antibody, DIS Antibody, RP11-437A18.1 Antibody

Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation By similarity.

Requested From: 
Date Requested: 5/28/2018

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