Bacteria Diphtheria Toxin

Mouse

Bacteria (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

8G1

Unconjugated

Protein A purified

Unmodified

Native

Recognizes diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kD, it is then processed to form A and B fragments both of which appear to be required for toxicity. 3710-0100 is specific for the intact toxin/toxoid and does not react with free A or B subunits.

• ELISA

PBS, 0.1% Sodium Azide

Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P00587 NCBI: P00587