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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DIO3 Antibody (Internal, Biotin) LS‑C142485
DIO3 antibody LS-C142485 is a biotin-conjugated rabbit polyclonal antibody to DIO3 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C142485-100
100 µl
Unavailable

Popular DIO3 Products

Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

DIO3 antibody LS-C142485 is a biotin-conjugated rabbit polyclonal antibody to DIO3 from human, mouse, rat and other species. Validated for WB.
About DIO3
The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. NM_001362

DIO3 Antibody, 5DIII Antibody, D3 Antibody, DIOIII Antibody, ITDI3 Antibody, TXDI3 Antibody, Type-III 5 deiodinase Antibody, Type-III 5-deiodinase Antibody, Type 3 DI Antibody


Specifications

Target
Rat DIO3
Host
Rabbit
Reactivity
Rat, Human, Mouse, Hamster, Rabbit (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.5 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
DIO3 antibody was raised against synthetic peptide made to an internal portion of the rat protein (within residues 250-300). [Swiss-Prot# P49897]. Percent identity by BLAST analysis: Human (93%).
Epitope
Internal
Specificity
Dio3.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.05% sodium azide
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Dio3 Antibody - Detection of Dio3 in rat placenta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Dio3 Antibody - Detection of Dio3 in rat placenta. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Dio3 Antibody - Detection of Dio3 in rat placenta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Dio3 Antibody - Detection of Dio3 in rat placenta. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Dio3 Antibody - Detection of Dio3 in rat placenta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Dio3 Antibody - Detection of Dio3 in rat placenta. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Dio3 Antibody - Detection of Dio3 in rat placenta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Dio3 Antibody - Detection of Dio3 in rat placenta. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/22/2018

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