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Anti-DIABLO / SMAC Antibody LS-C148290

Catalog Size Price
LS-C148290-50 50 µl Unavailable

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78 DIABLO / SMAC Antibodies

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Anti-DIABLO / SMAC Antibody (aa222-237) IHC-plus™ LS-B1350
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Anti-DIABLO / SMAC Antibody (clone 79-1-83) IHC-plus™ LS-B3668
Mouse Monoclonal [clone 79-1-83] (IgG2b) to Human DIABLO / SMAC
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Anti-DIABLO / SMAC Antibody (HRP) LS-C673953
Rabbit Polyclonal (IgG) to Human DIABLO / SMAC
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Anti-DIABLO / SMAC Antibody (FITC) LS-C673954
Rabbit Polyclonal (IgG) to Human DIABLO / SMAC
FITC Conjugated

100% Guaranteed
Rabbit Polyclonal to Human DIABLO / SMAC
Human, Mouse, Rat, Gerbil
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation


Human, Mouse, Rat, Gerbil (tested or 100% immunogen sequence identity)


  • IHC - Paraffin (1:1000 - 1:5000)
  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation (1:50 - 1:200)

Specificity and Use

DIABLO / SMAC antibody was raised against full length recombinant human SMAC.


Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.


Q9NR28 NM_019887 NP_063940.1

DIABLO Antibody, DFNA64 Antibody, DIABLO-S Antibody, Diablo homolog, mitochondrial Antibody, SMAC3 Antibody, Mitochondrial Smac protein Antibody, SMAC Antibody

Second mitochondria-derived activator of caspase (SMAC) has been implicated in the activation of apoptosis in response to cell stress. SMAC promotes CASP9 activation by binding to IAPs and removing their inhibitory activity. The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes.


Formalin-fixed, paraffin-embedded tissue section of human plasmacytoma (a mature B cell lymphoma) stained for Smac/DIABLO using LS-C148290 at 1:2000. Intense nuclear staining is observed. Hematoxylin-Eos in counterstain.


Formalin-fixed, paraffin-embedded human colon stained for Smac/DIABLO using LS-C148290 at 1:2000. A, normal colon. B and C, colon carcinoma. Only trace Smac/DIABLO immunoreactivity is seen in normal colonic epithelium (A), which is seen in the apical, foveolar cells. In contrast, strong immunoreactivity is observed in nuclear (B) and cytoplasmic (C) locations in the colon carcinoma specimen. Hematoxylin-Eosin counterstain.

Western blot

Western blot
Western blot of Smac/DIABLO human tissues and cell lines using LS-C148290 at 1:2000. Legend. SMAC: full-length recombinant smac. RS1846 and Jurkat are tumor cell lines. All tissues are from normal donors except colon carcinoma (Colon Ca). SMAC expression was detected in all samples except spleen and normal colon.

Requested From: 
Date Requested: 3/22/2018

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