DIABLO / SMAC

diablo, IAP-binding mitochondrial protein

Second mitochondria-derived activator of caspase (SMAC) has been implicated in the activation of apoptosis in response to cell stress. SMAC promotes CASP9 activation by binding to IAPs and removing their inhibitory activity. The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes. Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/caspase-9 pathway. Smac is an antagonist of the X-linked inhibitor of apoptosis (XIAP) - the most potent caspase inhibitor of all known inhibitor of apoptosis-family members. Smac promotes apoptosis by eliminating the inhibitory effect of inhibitor-of-apoptosis (IAPs) through physical interactions.

☰ Filters

Products

Antibodies (55)

Proteins (11)

ELISA Kits (5)

Type

Over-Expression Lysate (5)

Primary (55)

Recombinant (6)

Sandwich (5)

Target

DIABLO / SMAC (71)

Reactivity

Human (59)

Mouse (21)

Rat (17)

Bovine (3)

Chimpanzee (3)

Gerbil (3)

Gibbon (3)

Hamster (1)

Horse (3)

Monkey (1)

Orangutan (3)

more less

Application

IHC (23)

IHC-Fr (1)

IHC-P (12)

WB (45)

ELISA (21)

ICC (3)

IF (11)

IP (13)

Peptide-ELISA (1)

Host

rabbit (46)

mouse (9)

Product Group

IHCPlus (4)

Isotype

IgG (33)

IgG1 (1)

IgG1 + IgG3 (1)

IgG2a,k (1)

IgG2b (3)

Clonality

monoclonal mc (10)

polyclonal pc (45)

Clone

001 (1)

2D12 (1)

78-1-118 (1)

79-1-83 (1)

AT19F2 (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (3)

Biotin Conjugated (3)

FITC Conjugated (2)

HRP Conjugated (2)

Preservative Free (4)

Unconjugated (48)

Epitope

C-Terminus (7)

aa1-55 (2)

aa199-212 (2)

aa225-239 (1)

aa56-239 (1)

Publications

No (71)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (2)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (7)

Species

Human (8)

Mouse (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Human DIABLO / SMAC (Sandwich ELISA) ELISA Kit - LS-F186

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.12 - 30 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$840

Select

IHC-plus™ DIABLO / SMAC Antibody (clone 79-1-83) LS-B3668

(4.0) Rating

Antibody:

DIABLO / SMAC Mouse anti-Human Monoclonal (79-1-83) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ DIABLO / SMAC Antibody LS-B1350

(4.0) Rating

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.05 mg/$460

Select

Mouse DIABLO / SMAC Protein (Recombinant 6His, N-terminus) (Ala54-Asp237) - LS-G26434

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

21 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

Select

DIABLO / SMAC Antibody LS-C4

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$460

Select

IHC-plus™ DIABLO / SMAC Antibody (aa1-55, clone 78-1-118) LS-B221

(4.0) Rating

Antibody:

DIABLO / SMAC Mouse anti-Human Monoclonal (aa1-55) (78-1-118) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.2 ml/$460

Select

DIABLO / SMAC Antibody LS-C10206

Antibody:

DIABLO / SMAC Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$702

Select

DIABLO / SMAC Antibody LS-C484794

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

DIABLO / SMAC Antibody (clone 001, Preservative Free) LS-C820670

Antibody:

DIABLO / SMAC Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

IHC-plus™ DIABLO / SMAC Antibody (aa199-212) LS-B6439

(4.0) Rating

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal (aa199-212) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

DIABLO / SMAC Antibody LS-C490533

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

DIABLO / SMAC Antibody (aa56-239) LS-C408072

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal (aa56-239) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

DIABLO / SMAC Antibody LS-C393459

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$386

Select

DIABLO / SMAC Antibody LS-C809632

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

DIABLO / SMAC Antibody LS-C665084

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

DIABLO / SMAC Antibody LS-C89087

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$546

Select

DIABLO / SMAC Antibody LS-C148289

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Gerbil, Human

Applications:

IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$386

Select

DIABLO / SMAC Antibody LS-C401032

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

DIABLO / SMAC Antibody LS-C404289

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

DIABLO / SMAC Antibody LS-C332171

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

DIABLO / SMAC Antibody LS-C484793

Antibody:

DIABLO / SMAC Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

Select

DIABLO / SMAC Antibody LS-C19112

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$567

Select

DIABLO / SMAC Antibody LS-C358711

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

50 µl/$393

Select

DIABLO / SMAC Antibody LS-C358712

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Gerbil, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

50 µl/$393

Select

DIABLO / SMAC Antibody LS-C358713

Antibody:

DIABLO / SMAC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Gerbil, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

50 µl/$393

Viewing 1-25 of 71 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.