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Anti-DHX58 / LGP2 Antibody (aa35-84) LS-C110169


Wt. Vol. Conc. Price
50 µg - - Unavailable

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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human DHX58 / LGP2
Human, Monkey, Bat, Guinea pig, Horse, Pig
Western blot (applications tested for the base form of this product only)


Human DHX58 / LGP2
Human, Monkey, Bat, Guinea pig, Horse, Pig (tested or 100% immunogen sequence identity)
Mouse, Rat, Bovine, Dog, Rabbit (at least 90% immunogen sequence identity)
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified


  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

DHX58 / LGP2 antibody was raised against synthetic peptide located between aa35-84 of human DHX58 (Q96C10, NP_077024). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Panda, Bat, Horse, Pig, Guinea pig (100%); Orangutan, Galago, Elephant, Dog, Bovine, Rabbit (92%); Mouse, Rat (90%); Marmoset (85%).
LS-E13078 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C110169. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human DHX58
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.


Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About DHX58 / LGP2

Q96C10 NM_024119 NP_077024.2

DHX58 Antibody, D11LGP2 Antibody, D11lgp2e Antibody, Protein D11Lgp2 homolog Antibody, LGP2 Antibody, RIG-I-like receptor 3 Antibody, RNA helicase LGP2 Antibody, RLR Antibody, Ortholog of mouse D11lgp2 Antibody, RIG-I-like receptor LGP2 Antibody, RLR-3 Antibody

Acts as a regulator of DDX58/RIG-I and IFIH1/MDA5 mediated antiviral signaling. Cannot initiate antiviral signaling as it lacks the CARD domain required for activating MAVS/IPS1-dependent signaling events. Can have both negative and positive regulatory functions related to DDX58/RIG-I and IFIH1/MDA5 signaling and this role in regulating signaling may be complex and could probably depend on characteristics of the infecting virus or target cells, or both.

Western blot

Western blot
DHX58 antibody LS-C110169 Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 4/24/2017

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