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DHX15 is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns.
Gene Name: | DEAH (Asp-Glu-Ala-His) box helicase 15 |
Synonyms: | DHX15, ATP-dependent RNA helicase #46, DEAH box protein 15, DDX15, DEAD/H box-15, PRP43, PRPF43, RNA helicase 2, DBP1, PrPp43p |
Target Sequences: | NM_001358 NP_001349.2 O43143 |
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