Broad DHEA / Dehydroepiandrosterone

Mouse

Broad (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

DHEA(-3):1-19.1 (BGN/117/1191)

Unconjugated

Affinity purified

Unmodified

DHEA-3-HS-BSA conjugate.

Detects dehydroepiandrosterone (DHEA) a steroid prohormone which is the precursor of all sex steroids. DHEA is produced primarily by the adrenal glands, and together with its ester DHEA-sulphate (DHEAS), has been implicated in a wide range of physiological roles including aging, immunology, memory and obesity. In particular, DHEA and DHEAS differentially regulate growth-factor induced proliferation of chromaffin cells, and are thought to affect neurogenesis, neuronal survival, and neuronal stem cell proliferation. Blood measurements of DHEAS/DHEA are useful to detect excess adrenal activity due to adrenal cancer or hyperplasia, including certain forms of congenital adrenal hyperplasia.

• ELISA (1:1000 - 1:10000)

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

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