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DGAT1

diacylglycerol O-acyltransferase 1

Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.

Gene Name: diacylglycerol O-acyltransferase 1
Synonyms: DGAT1, ACAT-related gene product 1, ACAT related gene product 1, ARGP1, ARAT, DGAT, Diglyceride acyltransferase, AGRP1
Target Sequences: NM_012079 NP_036211.2 O75907

Publications (3)

1
High fatty acid availability after exercise alters the regulation of muscle lipid metabolism. Newsom SA, Schenk S, Li M, Everett AC, Horowitz JF. Metabolism: clinical and experimental. 2011 60:852-9. [PubMed:20870251] [PMC:PMC3011035]
2
High muscle lipid content in obesity is not due to enhanced activation of key triglyceride esterification enzymes or the suppression of lipolytic proteins. Li M, Paran C, Wolins NE, Horowitz JF. American journal of physiology. Endocrinology and metabolism. 2011 300:E699-707. [PubMed:21285405] [PMC:PMC3074947]
3
DGAT1 mutation is linked to a congenital diarrheal disorder. Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV. The Journal of clinical investigation. 2012 122:4680-4. (WB; Mouse) [PubMed:23114594] [PMC:PMC3533555]

☰ Filters
Antibodies (30)
ELISA Kits (5)
Proteins (4)
Over-Expression Lysate (2)
Primary (30)
Recombinant (2)
Sandwich (5)
DGAT1 (39)
Human (31)
Mouse (16)
Rat (15)
Bat (1)
Bovine (10)
Chimpanzee (3)
Dog (2)
Goat (2)
Hamster (1)
Horse (1)
Monkey (2)
Pig (2)
Rabbit (4)
Sheep (5)
Zebrafish (5)
IHC (3)
IHC-P (3)
WB (26)
ELISA (5)
IP (1)
Peptide-ELISA (3)
rabbit (28)
goat (2)
Product Group
IHCPlus (3)
IgG (9)
polyclonal pc (30)
96-Well Strip Plate (5)
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (13)
aa180-427 (8)
aa200-300 (6)
aa78-127 (4)
aa1-90 (2)
aa280-318 (2)
Internal (1)
aa1-62 (1)
aa119-139 (1)
aa217-229 (1)
aa67-79 (1)
No (39)
Cell Lysates (1)
Plasma (4)
Serum (4)
Tissue Homogenates (5)
10His, N-terminus + Myc, C-terminus (1)
His (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Purified (1)
DGAT1 Antibody - Anti-DGAT1 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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DGAT1 Goat anti-Human Polyclonal (aa217-229) Antibody
Mouse, Goat, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
DGAT1 Antibody - Anti-DGAT1 / DGAT antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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DGAT1 Goat anti-Human Polyclonal (aa67-79) Antibody
Rabbit, Mouse, Goat, Dog, Sheep, Bovine, Rat, Pig, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
DGAT1 Antibody - Detection of DGAT1 in HepG2 lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DGAT1 Rabbit anti-Human Polyclonal (aa200-300) Antibody
Zebrafish, Rat, Mouse, Bovine, Human
WB
Unconjugated
0.1 ml/$386
DGAT1 Antibody - Detection of DGAT1 in HepG2 lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DGAT1 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody
Zebrafish, Rat, Mouse, Bovine, Human
WB
Biotin Conjugated
0.1 ml/$416
DGAT1 Antibody - Detection of DGAT1 in HepG2 lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DGAT1 Rabbit anti-Human Polyclonal (aa200-300) (DY488) Antibody
Zebrafish, Rat, Mouse, Bovine, Human
WB
DY488 Conjugated
0.1 ml/$416
DGAT1 Antibody - Detection of DGAT1 in HepG2 lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DGAT1 Rabbit anti-Human Polyclonal (aa200-300) (DY650) Antibody
Zebrafish, Rat, Mouse, Bovine, Human
WB
DY650 Conjugated
0.1 ml/$416
DGAT1 Antibody - Detection of DGAT1 in HepG2 lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DGAT1 Rabbit anti-Human Polyclonal (aa200-300) (DY550) Antibody
Zebrafish, Rat, Mouse, Bovine, Human
WB
DY550 Conjugated
0.1 ml/$416
DGAT1 Antibody - Western blot analysis of extracts of Mouse heart tissue, using DGAT1 antibody.
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DGAT1 Rabbit anti-Human Polyclonal (aa200-300) Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
DGAT1 Rabbit anti-Human Polyclonal (aa1-90) Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
DGAT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.1 kDa
20 µg/$150
DGAT1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
DGAT1 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 µg/ml
Select
DGAT1 Rabbit anti-Human Polyclonal (aa1-62) Antibody
Human
ELISA, IHC-P
Unconjugated
50 µg/$460
Select
DGAT1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
DGAT1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
DGAT1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
DGAT1 Rabbit anti-Human Polyclonal (aa119-139) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DGAT1 Antibody - Western blot of Mouse Heart. Dgat1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DGAT1 Rabbit anti-Mouse Polyclonal (aa78-127) Antibody
Mouse
WB
Unconjugated
100 µl/$424
DGAT1 Antibody - Western blot of Mouse Heart. Dgat1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DGAT1 Rabbit anti-Mouse Polyclonal (aa78-127) (HRP) Antibody
Rabbit, Mouse, Sheep, Bovine, Rat, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
DGAT1 Antibody - Western blot of Mouse Heart. Dgat1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DGAT1 Rabbit anti-Mouse Polyclonal (aa78-127) (Biotin) Antibody
Rabbit, Mouse, Sheep, Bovine, Rat, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
DGAT1 Antibody - Western blot of Mouse Heart. Dgat1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DGAT1 Rabbit anti-Mouse Polyclonal (aa78-127) (FITC) Antibody
Rabbit, Mouse, Sheep, Bovine, Rat, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
Select
DGAT1 Rabbit anti-Human Polyclonal (aa1-90) Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DGAT1 Antibody - Western blot of recombinant DGAT1 / DGAT.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DGAT1 Rabbit anti-Human Polyclonal (aa180-427) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
DGAT1 Antibody
Select
DGAT1 Rabbit anti-Human Polyclonal (aa200-300) Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
DGAT1 Antibody
Select
DGAT1 Rabbit anti-Human Polyclonal (aa280-318) Antibody
Rat, Human
WB
Unconjugated
100 µg/$575
DGAT1 Antibody - DGAT1 antibody Western blot. All lanes: Anti DGAT1 at 0.5 ug/ml. Lane 1: Rat Kidney Tissue Lysate at 50 ug. Lane 2: HELA Whole Cell Lysate at 40 ug. Predicted band size: 60 kD. Observed band size: 60 kD.
Select
DGAT1 Rabbit anti-Human Polyclonal (aa280-318) Antibody
Rat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 39 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).