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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DES / Desmin Antibody (clone 10H7D2) IHC‑plus™ LS‑B1579
Note: This antibody replaces LS-C41446
Desmin antibody LS-B1579 is an unconjugated mouse monoclonal antibody to human Desmin (DES). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B1579-50
50 µl (1 mg/ml)
Unavailable

Popular DES / Desmin Products

Anti-DES / Desmin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2264 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Formalin-fixed, paraffin-embedded human leiomyoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of muscle cells.
Species: Human, Baboon, Monkey, Rat, Bovine, Cat, Dog, Hamster, Chicken
Applications: IHC, IHC - Paraffin, Immunofluorescence
Formalin-fixed, paraffin-embedded human leiomyoma stained with peroxidase-conjugate and AEC. Note cytoplasmic staining of tumor cells.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-DES / Desmin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4463 concentration 3.75 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-DES / Desmin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5553 dilution 1:100.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot

Product Description

Desmin antibody LS-B1579 is an unconjugated mouse monoclonal antibody to human Desmin (DES). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
About DES / Desmin
Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. P17661 NM_001927 NP_001918.3

DES Antibody, ARVC7 Antibody, ARVD7 Antibody, CMD1I Antibody, CSM1 Antibody, CSM2 Antibody, MFM1 Antibody, SCPNK Antibody, Desmin Antibody, Intermediate filament protein Antibody


Specifications

Target
Human DES / Desmin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [10H7D2]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:1000 - 1:2000)
  • IHC - Frozen (1:1000 - 1:2000)
  • Western blot (1:100 - 1:500)
  • ELISA (1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
DES / Desmin antibody was raised against purified recombinant fragment of Desmin expressed in E. Coli.
Specificity
Human
Usage
Immunohistochemistry: LS-B1579 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1579 was determined to be 1:1000-1:2000.
Presentation
Purified antibody in PBS containing 0.03% sodium azide
Storage
Short term: 4°C; Long term: -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-DES / Desmin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1579 dilution 1:1000.
Anti-DES / Desmin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1579 dilution 1:1000.

Western blot

Western blot using Desmin mouse monoclonal antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Desmin cDNA (2).
Western blot using Desmin mouse monoclonal antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Desmin cDNA (2).

Immunohistochemistry

Anti-DES / Desmin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1579 dilution 1:1000.
Anti-DES / Desmin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1579 dilution 1:1000.

Western blot

Western blot using Desmin mouse monoclonal antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Desmin cDNA (2).
Western blot using Desmin mouse monoclonal antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Desmin cDNA (2).

Immunohistochemistry

Anti-DES / Desmin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1579 dilution 1:1000.
Anti-DES / Desmin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1579 dilution 1:1000.

Western blot

Western blot using Desmin mouse monoclonal antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Desmin cDNA (2).
Western blot using Desmin mouse monoclonal antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Desmin cDNA (2).

Immunohistochemistry

Anti-DES / Desmin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1579 dilution 1:1000.
Anti-DES / Desmin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1579 dilution 1:1000.

Western blot

Western blot using Desmin mouse monoclonal antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Desmin cDNA (2).
Western blot using Desmin mouse monoclonal antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Desmin cDNA (2).


Requested From: 
Date Requested: 6/20/2018

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