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DEPDC1
DEP domain containing 1
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
| Gene Name: | DEP domain containing 1 |
| Synonyms: | DEPDC1, DEP domain containing 1, DEPDC1A, DEP.8, SDP35, DEPDC1-V2 |
| Target Sequences: | NM_017779 NP_060249.2 Q5TB30 |
Publications (2)
1
DEP domain containing 1 suppresses apoptosis via inhibition of A20 expression, which activates the nuclear factor ?B signaling pathway in HepG2 cells. Li A, Wang Q, He G, Jin J, Huang G. Oncology letters. 2018 July;16:949-955. (Human)
[Full Text Article]
[PubMed:29963168]
[PMC:PMC6019891]
Related Antibodies: LS-C167364.
2
Targeted interfering DEP domain containing 1 protein induces apoptosis in A549 lung adenocarcinoma cells through the NF-?B signaling pathway. Wang Q, Li A, Jin J, Huang G. OncoTargets and therapy. 2017 September;10:4443-4454. (Human)
[Full Text Article]
[PubMed:28979136]
[PMC:PMC5602701]
Related Antibodies: LS-C167364.
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Antibodies
(17)
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Type
Over-Expression Lysate
(2)
Primary
(17)
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Target
DEPDC1
(20)
Reactivity
Human
(17)
Rat
(3)
Bovine
(3)
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(3)
Gibbon
(3)
Guinea pig
(3)
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IHC
(7)
IHC-P
(1)
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(17)
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(12)
IF
(5)
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rabbit
(11)
mouse
(6)
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(6)
IgG2a,l
(6)
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monoclonal mc
(6)
polyclonal pc
(11)
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(2)
Azide-free
(1)
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(3)
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(3)
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(3)
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(2)
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(4)
Epitope
aa10-38
(7)
aa287-336
(4)
aa93-187
(1)
Publications
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(19)
Yes
(1)
Tag
GST, N-terminus
(1)
Myc-DDK (Flag)
(2)
Species
Human
(2)
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293T Cells
(1)
HEK 293 Cells
(1)
Wheat Germ Extract
(1)
DEPDC1 Rabbit anti-Human Polyclonal (aa10-38) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
DEPDC1 Rabbit anti-Human Polyclonal (aa10-38) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
DEPDC1 Rabbit anti-Human Polyclonal (aa10-38) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
DEPDC1 Rabbit anti-Human Polyclonal (aa10-38) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
DEPDC1 Rabbit anti-Human Polyclonal (aa10-38) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
DEPDC1 Rabbit anti-Human Polyclonal (aa10-38) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
DEPDC1 Rabbit anti-Human Polyclonal (aa10-38) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
DEPDC1 Mouse anti-Human Monoclonal (aa93-187) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
DEPDC1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
DEPDC1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
DEPDC1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
DEPDC1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
DEPDC1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
DEPDC1 Rabbit anti-Human Polyclonal (aa287-336) Antibody
Human
WB
Unconjugated
100 µl/$424
DEPDC1 Rabbit anti-Human Polyclonal (aa287-336) (HRP) Antibody
Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human
WB
HRP Conjugated
100 µl/$469
DEPDC1 Rabbit anti-Human Polyclonal (aa287-336) (Biotin) Antibody
Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human
WB
Biotin Conjugated
100 µl/$469
DEPDC1 Rabbit anti-Human Polyclonal (aa287-336) (FITC) Antibody
Guinea pig, Bovine, Rat, Chimpanzee, Gibbon, Human
WB
FITC Conjugated
100 µl/$469
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
293T Cells
Myc-DDK (Flag)
61.3 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
61.3 kDa
100 µg/$494
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